Mehmet GÜNEŞ, Aslıhan Okan İBİLOĞLU, Mehmet Cemal KAYA, Süleyman DEMİR

Şizofrenide paliperidon kullanımı ile ilişkili mani: Bir olgu sunumu

Paliperidon şizofreni tedavisi için kullanılan atipik antipsikotik bir ilaçtır. Paliperidon tedavisi sırasında bazı nadir yan etkiler görülebilmektedir. Literatürde antipsikotiklerin indüklediği hipomanik ve manik belirtiler ile ilgili çok sayıda olgu sunumu olmasına rağmen paliperidonun indüklediği mani olguları kısıtlı sayıda yayınlanmıştır. Bu olguda 9 mg/gün paliperidon tedavisi başlandıktan sonra mani belirtileri görülen, paliperidon kesilip aripiprazol başlanması ile mani belirtilerinin hızla düzeldiği bir şizofreni hastası sunulmaktadır. Klinisyenler şizofreni hastalarında, paliperidon tedavisinin mani belirtilerini tetikleyebileceğini göz önünde tutmalıdır

Mania associated with paliperidone treatment in schizophrenia: A case report

Paliperidone is an atypical antipsychotic drug used to treat schizophrenia. Paliperidone can cause some rare side effects during treatment. Despite many publications of mania and hypomania induced by antipsychotics, mania cases induced by paliperidone are few in the literature. In this case a schizophrenia patient showing symptoms of mania during usage of paliperidone with a dose of 9 mg/day in which the symptoms rapidly disappeared after discontinuation of paliperidone and initiation of aripiprazole was reported. Clinicians should be aware of that Paliperidone treatment may trigger mania symptoms.

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