Arda IŞIK, İsmail DEMİRYILMAZ, İsmayil YILMAZ, Kemal PEKER, Abdullah İNAL, Mustafa EMİROĞLU

Intragastric manometric measurements of patients with hiatal hernia: A prospective controlled study

Amaç: Hiatus hernisi, diafragmanın özofageal hiatusdaki anatomik zayıflık ya da defekt nedeniyle intraabdominal organların toraksa çıkışı olarak tanımlanabilir. Bu çalışmanın amacı kardio özofageal yetmezlikli ve hiatal hernili hastaların intragastrik basınç düzeylerini incelemekti.Yöntemler: Çalışmaya 81 hasta dâhil edildi. Hastaların 42 (%51,9)'si erkek iken 39 (%48,1)'u bayan idi. Yaş ortalamaları 42 yıl olarak tespit edildi. Hastalardan iki grup oluşturuldu. Bir grup (G1) sağlıklı gönüllü hastalardan oluşur iken, ikinci grup (G2) hiatal herni hali olan hastalardan oluşturuldu. Gastroskopiden sonra, tüm hastalara su perfüzyon sistemli kateter kullanılarak gastrik ve özofageal manometrik ölçümler yapıldı.Bulgular: Ortalama intragastrik basınç düzeyi kontrol grubu için 1,308 mmHg iken, hasta grubu için bu değer -0,105 mmHg olarak ölçüldü. Kontrol grubunda distal özofageal gastrik basınç düzeyi 13,143 mmHg iken hasta grubunda bu oran 11,65 mmHg olarak, üst özofageal sfinkter basınç düzeyi sırayla 35,273 mmHg ve 27,211 mmHg olarak ölçüldü. Hiatal herni hali mevcut olan G2 için yapılan 24 saatlik pH monitörizasyonunda %26,8 hastada, reflü fizyolojik sınırlarda iken %73,2 hastada reflü hali patolojik sınırlarda tespit edildi. Gruplar arası intragastrik ve distal özofageal basınç düzeyleri açısından yapılan ikili karşılaştırmalarda sonuçlar istatistiksel olarak anlamlı idi (p

Hiatal Hernili hastalarda intragastrik manometrik ölçümler: Prospektif kontrollü bir çalışma

Objective: Hiatal hernia is a disorder in which abdominal contents, especially gastroesophageal junction and proximal stomach are displaced through an incompetent esophageal hiatus into mediastinum. Aim of this study is to investigate the relationship betweeen intragastric pressure and incompetent cardioesophageal sphincter and hiatal hernia. Methods: The sample is composed of 81 individuals; 51.9% of which are male (n: 42) and 48.1% of which are female (n: 39) with median age of 42.00. Two groups have been constituted: A control group of healthy volunteers (G1) and a patient group with hiatal hernia (G2). After gastroscopy, all patients and controls underwent gastric and esophageal manometry using a water perfused catheter Results: Mean intragastric pressure was 1,308 mmHg for G1 and, -0,105 mmHg for G2. Mean lower esophageal pressure were 13,143 mmHg and 11,65 mmHg, and upper esophageal pressure were 35,273 mmHg and 27,211 mmHg for G1 and G2, respectively. 24 hour pH metry test revealed 26.8% physiologic gastroesophageal reflux and 73.2% pathologic gastroesophageal reflux in G2. There were statistically significant difference between two groups for mean intragastric pressure (p

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