Hirsutizm nedeniyle başvuran hastaların tanısal açıdan değerlendirilmesi

Amaç: Hirsutizm, kadınlarda androjen duyarlı bölgelerde erkeklerdekine benzer şekilde terminal kılların bulunmasıdır. Çalışmamızda hirsutizm şikayeti olan hastalarda etyolojiye yönelik araştırma yaparak hirsutizme neden olan hastalıkların sıklığının belirlenmesi amaçlanmıştır.Yöntemler: Çalışmaya Mustafa Kemal Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı polikliniğine hirsutizm nedeniyle başvuran 40 hasta alındı. Hastalarla ilgili demografik, klinik ve laboratuvar parametreler incelendi.Bulgular: Çalışma sonucu hirsutizmin en sık nedeninin polikistik over sendromu olduğunu göstermiştir. İkinci en sık neden idiopatik hirsutizm bulunmuştur.Sonuç: Bu çalışmayla birlikte etnik ve kültürel farklılığın yoğun olduğu bölgemizde ilk olarak hirsutizmin etyolojik faktörleri incelenmiştir. Cushing sendromu, hiperprolaktinemi, non klasik adrenal hiperplazi, androjen salgılayan tümörler gibi nadir görülen durumlarda hirsutizmin ayrıcı tanısında düşünülmelidir.

Diagnostic evaluation of patients presenting with hirsutism

Objective: Hirsutism, similar to men, is the presence of terminal hairs in androgen-to sensitive areas in women. The present report aimed to study etiology and determine the prevalence of the diseases that causes hirsutism in these patients.Methods: In this study, total number of 40 patients who admitted because of hirsutism to Department of Endocrinology and Metabolism clinic was enrolled. Demographic, clinical and laboratory parameters of the patients were evaluated.Results: Result of the study showed that polycystic ovary syndrome is the most common cause of hirsutism. The second most common cause was found as idiopathic hirsutism.Conclusion: By the present study, etiologic factors of hirsutism were examined firstly in our region in which Ethnic and cultural diversity is concentrated. In rare cases like Cushing's syndrome, hyperprolactinemia, non-classic adrenal hyperplasia, androgen-secreting tumors should be considered in the differential diagnosis of hirsutism.

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Journal of Clinical and Experimental Investigations-Cover
  • Başlangıç: 2010
  • Yayıncı: Sağlık Araştırmaları Derneği
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