Özlem MORALOĞLU, Yasemin TAŞÇI, Rahime FINDIK BEDİR, Miray ESER SEKKİN, Jale KARAKAYA, Ebru ERSOY

Kloasma, II. Trimester Tarama Testleriyle Önceden Öngörülebilir Mi?

Amaç: Gebelikte melesma oluşumunun, artan hormon düzeyleri ile ilişkisi aşikardır. Amacımız gebe kadınlardaki melesma oluşumunun II. trimester tarama testindeki (E3,AFP, β-HCG ) hormon düzeyleri ile ilişkisini araştırmak. Gereç ve Yöntemler: Çalışmaya 91 primigravid miad gebe dahil edildi. Bunların 47si kloasması olan ve 44ü de kloasması olmayan gebelerden oluşuyordu. İki grup, E3,AFP, β-HCG düzeyleri, ten rengi, aile öyküsü, alerji öyküsü, sigara, oral kontraseptif (OKS) ve güneş koruyucu kullanımı, vitamin kullanımı, anne mesleği ve bebek cinsiyeti açısından karşılaştırıldı. Bulgular: Her iki grupta hormon düzeyleri açısından fark izlenmedi. Kloasması olan grupta erkek bebek oranı ve aile öyküsü oranı istatiksel olarak anlamlı yüksek tespit edildi (p=0,015;p=0,011). Sonuç: II. trimester tarama testindeki hormon düzeyleri melesma gelişimi ile ilgili bize bilgi vermemektedir. Melesma oluşumunda sadece gebelikte artan hormonların değil, diğer faktörlerin de etkisi vardır. Bunların içinde de en önemlisi aile öyküsüdür. Sanılanın aksine melesma daha çok erkek bebek cinsiyeti ile ilgili gözükmektedir.

Can Cloasma Be Predicted By 2nd Trimester Screening Tests?

Aim: The relationship between melasma formation and increasing hormones during pregnancy is apperent. Our aim is to research the relation of pregnant women s melasma formation and hormone levels of second trimester scanning test (E3, AFP, β-HCG). Material and Methods: 91 primigravide miad pregnants is included to study. 47 of pregnants had cloasma and 44 of pregnants had not cloasma. Two groups are compared for E3, AFP, β-HCG levels, skin colour, family story, allergy story, cigarette usage, oral contraceptive (OKS) usage and sun protective usage, vitamin usage, mother profession and baby sex. Results: No difference is detected between two groups for hormon levels. Higher male baby and family story rate were statistically significant for the group with cloasma (p=0,015, p=0,011). Conclusion: The hormone levels of second trimester scanning test do not inform for melasma formation. Not only increasing hormone levels during pregnancy but also other factors have affect on melasma formation. The most important of them is family story. Contrary to popular belief, melasma has more relation with male sex.

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