İzole İntrauterin Gelişme Kısıtlılığı Olan Gebeliklerde Tam Kan Sayım Parametreleri

Amaç: Çalışmamızda intrauterin gelişme kısıtlılığı İUGK olan gebelikler ile sağlıklı gebelikler arasında tam kan sayım parametrelerini karşılaştırılması ve İUGK varlığında hematolojik değişikliklerin istenmeyen gebelik sonuçları üzerinde belirleyici değerinin olup olmadığını araştırılması hedeflenmiştir.Gereç ve Yöntemler: İUGK ile komplike 35 gebenin ve 105 sağlıklı kontrolün ortalama platelet hacmi OPH , platelet dağılım genişliği PDG , plateletcrit PCT , platelet büyük hücre oranı P-BHO ve kırmızı hücre dağılım genişliği KDG retrospektif olarak değerlendirilmiştir.Bulgular: IUGK olan gebelerde kontrol grubuna göre, OPH ortalama 11.21 ± 0.99 vs. 9.99 ± 0.84; p

Complete Blood Count Indices in Pregnancies With Isolated Intrauterine Growth Restriction

Aim: Our aim was to compare the complete blood count indices in intrauterine growth restriction IUGR with healthy pregnant controls and to investigate whether any hematological changes have predictive value for the prediction of adverse pregnancy outcomes in IUGR.Material and Methods: Mean platelet volume MPV , platelet distribution width PDW , plateletcrit PCT , platelet large cell ratio P-LCR and red cell distribution width RDW levels of 35 pregnant women with isolated IUGR and 105 healthy pregnant women were retrospectively evaluated.Results: Women with IUGR had significantly higher MPV mean 11.21 ± 0.99 vs. 9.99 ± 0.84; P

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  • ACOG Practice Bulletin. Fetal growth restriction. Obstetrics and Gynecol- ogy 2013; 121:1122-7.
  • Friedman AM, Cleary KL. Prediction and prevention of ischemic placental disease. Seminars in Perinatology 2014; 38:177-82.
  • Srinivas SK, Edlow Ag, Neff PM, Sammel MD, Andrela CM, Elovitz MA. Rethinking IUGR in preeclampsia: dependent or independent of maternal hypertension? J Perinatol 2009;29:680-4.
  • Ananth CV. Ischemic placental disease: A unifying concept for pre- eclampsia, intrauterine growth restriction, and placental abruption. Sem- inars in Perinatology 2014;38:131-2.
  • Chu SG, Becker RC, Berger PB, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and metaanalysis. J Thromb Haemost 2010;8:148-156.
  • Patel KV, Ferrucci L, Ershler WB, Longo DL, Guralnik JM. Red blood cell distribution width and the risk of death in middle-aged and older adults. Arch Intern Med 2009;169:515-523.
  • Ravindran R, Krishnan LK. Increased platelet cholesterol and decreased percentage volume of platelets as a secondary risk factor for coronary artery disease. Pathophysiol Haemost Thromb 2007;36:45-51.
  • Wilson BJ, Watson MS, Prescott GJ, Sunderland S, Campbell DM, Hannaford P et al. Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: Results from cohort study. BMJ 2003;326:845-52.
  • Piazze J, Gioia S, Cerekja A, Larciprete G, Argento T, Pizzulo S et al. Dop- pler velocimetry alterations related to platelet changes in third trimester pregnancies. Platelets 2007;18:11-5.
  • Gioia S, Piazze J, Ancheschi MM, Cerekja A, Alberini A, Giancotti A et al. Mean platelet volume: Association with adverse neonatal outcome. Platelets 2007;18:284-88.
  • Keskin Kurt R, Aras Z, Silfeler DB, Kunt C, Islimye M, Kosar O. Rela- tionship of Red Cell Distribution Width With the Presence and Severity of Preeclampsia. Clin Appl Thromb Hemost. Clin Appl Thromb Hemost. 2013 [Epub ahead of print]
  • Vagdatli E, Gounari E, Lazaridou E, Katsibourlia E, Tsikopoulou F, Labria- nou I. Platelet distribution width: a simple, practical and specific marker of activation of coagulation. Hippokratia 2010;14:28-32.
  • Kaya MG, Yarlioglues M, Gunebakmaz O, Gunturk E, Inanc T, Dogan A et al. Platelet activation and inflammatory response in patients with non-dipper hypertension. Atherosclerosis 2010;209:278–82.
  • Kamath S, Blann AD, Lip GY. Platelet activation: assessment and quanti- fication. Eur Heart J 2001;22:1561–71.
  • Giles H, Smith RE, Martin JF. Platelet glycoprotein IIb–IIIa and size are in- creased in acute myocardial infarction. Eur J Clin Invest 1994;24:69–72.
  • Wasiluk A, Dabrowska M, Osada J, Jasinska E, Laudanski T, Redzko S. Platelet indices in small for gestational age newborns. Adv Med Sci 2011;56:361-5.
  • Marumoto Y, Kaibara M, Murata T. Hemorheological studies on platelet counts and size in normal pregnancy and pregnancies with preeclampsia and intrauterine growth retardation. Nihon Sanka Fujinka Gakkai Zasshi 1989;41:1380-6.
  • Bilgic I, Dolu F, Senol K and Tez M. Prognostic significance of red cell distribution width in acute mesenteric ischemia. Perfusion 2014; [Epub ahead of print]
  • Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory bio- markers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133:628–632.
  • Jo YH, Kim K, Lee JH, et al. Red cell distribution width is a prognostic factor in severe sepsis and septic shock. Am J Emerg Med 2013;31:545– 548.
  • Trevisanuto D, Doglioni N, Altinier S, Zaninotto M, Plebani M, Zanardo V. High-sensitivity C-reactive protein in umbilical cord of small-for-gesta- tional-age neonates. Neonatology 2007;91:186-9.
  • Lausten-Thomsen U, Olsen M, Greisen G, Schmiegelow K. Inflammatory markers in umbilical cord blood from small-for-gestational-age new- borns. Fetal Pediatr Pathol 2014;33:114-8.
  • Garofoli F, Ciardelli L, Mazzucchelli I et al. The red cell distribution width (RDW): value and role in preterm, intrauterine growth restricted (IUGR), full-term infants. Hematology 2014;19-6:365-9
Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi-Cover
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2004
  • Yayıncı: -
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