Aydan MERTOĞLU, Ali Kadri ÇIRAK, Yelda VAROL, Gülistan KARADENİZ, Zeynep ÖNDEŞ, Serpil TEKGÜL, Görkem VAYISOĞLU ŞAHİN, Enver YALNIZ, Melih BÜYÜKŞİRİN, Dursun TATAR, Sami DENİZ, Emel CİRELİ, Ali KORKMAZ

Kronik Obstrüktif Akciğer Hastalığı Nedeniyle HastaneyeYatan Hastalarda Arteriyel Kan Gazının Yerine Venöz KanGazının Değeri

Amaç: Kılavuzlar, kronik obstrüktif akciğer hastalığı alevlenmelerinde arteriyel kan gazı analizinin kullanılmasını önermektedir, ancak arteriyel kan örneklemesi venöz kan örneklemesine göre daha zordur ve komplikasyon riski daha yüksektir. Bu çalışmanın amacı, kronik obstrüktif akciğer hastalığında venöz kan gazlarının arteriyel kan gazlarıyla korele olup olmadığını araştırmaktır. Gereç ve Yöntemler: Tek merkezli kesitsel olan çalışmada, kronik obstrüktif akciğer hastalığı bulunan hastaların arteriyel ve venöz kan gazı ölçümleri karşılaştırıldı. Arteriyel ve venöz parametreler arasındaki uyumun incelenmesi için Bland Altman analizi kullanıldı. Bulgular: Yüz hastada yapılan çalışmada kan gazı parametreleri pH, $HCO_3$ ve $PaCO_2$’nin venöz ve arteriyel farklılıkları 0 çizgisi civarındaydı ve hesaplanan uyum sınırlarının %95’i içinde rastgele dağılım gösteriyordu. Arteriyel ve venöz $HCO_3$ (p=0,050) ve PaCO2 (p=0,011) belirgin uyum gösterdi. Sonuç: Venöz $HCO_3$ ve $PaCO_2$ değerleri arteriyel değerlerle uyumludur ve kronik obstrüktif akciğer hastalığında arteriyel kan gazları yerine venöz kan örneklerinin kullanılabileceği sonucuna varıldı.

The Feasibility of Venous Blood Gas Instead of Arterial Blood Gas in Patients Hospitalized for Chronic Obstructive Pulmonary Diseases Acute Exacerbation

Objective: Guidelines recommend using arterial blood gas analysis in chronic obstructive pulmonary disease exacerbations (COPDE), but arterial blood sampling is more difficult than venous blood sampling and has higher risk of complications. The objective of the study is to investigate whether venous blood gasses correlate with arterial blood gasses in COPDE. Material and Methods: It was a one-center cross-sectional study. We compared arterial and venous blood gas measurements of patients with COPDE. We used Bland Altman analysis for correlation and agreement between arterial and venous parameters. Results: Among 100 patients studied, venous and arterial differences of blood gas parameters pH, $HCO_3$ , and $PCO_2$ were around the 0 line and were randomly distributed within 95% of the calculated compliance limits. Arterial and venous $HCO_3$ (p=0.050) and $PCO_2$ (p=0.011) showed significant agreement. Conclusion: Venous $HCO_3$ and $PCO_2$ values correlate with arterial values and we concluded that venous blood samples can be used instead of arterial blood gasses in COPDE.

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