Ferişte ÖZTÜRK, Sevgi ONAT, Hilal BATI, Sinem KARABULUT, Bora YÜKSEL

TEK TARAFLI HERPETİK STROMAL KERATİTLİ HASTALARIN SAĞLIKLI GÖZLERİNDE GÖZYAŞI İŞLEVİ

Bu çalışmanın amac tek taraflı latent stromal herpetik keratitli hastaların sağlıklı gözlerindeki gözyaşı işlevinin değerlendirilmesidir. Kornea bölümünden unilateral latent stromal herpetic keratitli 42 hasta ele alındı. Kontrol gurubu sağlıklı 25 kadın, 19 erkekten oluşmaktaydı. 5 dk geleneksel Schirmer I testi anestezisiz olarak kapaklar kapalıyken uygulandı. Her iki gurupta BUT süresi ölçüldü ve korneanın floressein boyanma özelliği değerlendirildi. Kontrol ve test grubunun yaş ortalamalarının karşılaştırmasında t testi kullanıldı. Cinsiyet,sigara alışkanlığı ve gözyaşı işlevi ile ilgili değerlerin karşılaştırılmasında ise ki kare testi kullanıldı.İki gurup arasında ortalama yaş, cinsiyet ve sigara içme oranları arasında istatistiksel anlamlı bir fark yoktu. Korneada floressein boyanma herpes gurubunda %31.7, kontrol gurubunda %6.8 oranında görüldü. Aradaki fark istatistiksel olarak anlamlı idi χ2: 8,604, p:0,005 . Ortalama Schirmer değeri herpes gurubunda 9.0±8.2mm, kontrol gurubunda 19.0±9.8mm p:0.000 . Ortalama BUT herpes gurubunda 13.8±14.5, kontrol gurubunda 21.8±12.7mm idi p:0.009 . İki gurup arasında HSV-1IgG,M or HSV-2IgG,M seropozitifliği açısından istatistiksel anlamlı fark bulunmadı. Unilateral latent stromal herpetic keratitli hastaların sağlıklı gözlerinde istirahat hali gözyaşı salgısında azalma, gözyaşı kırılma zamanında kısalma BUT , korneanın floressein boyanmasında artış saptanmıştır. Özetle bu gözler de kuru göz bulguları taşımaktadır

Anahtar Kelimeler:

Herpetik keratit, karşı göz, gözyaşı işlevi

TEAR FUNCTION IN THE HEALTHY EYES OF UNILATERAL LATENT HERPETIC STROMAL KERATITIS PATIENTS

This study was conducted to evaluate the tear function in the healthy eye of the patients with unilateral latent stromal herpetic keratitis. Fourty two patients with unilateral latent stromal herpetic keratitis were acquired from the cornea department. Control group consisted of 44 people including 25 women and 19 men. A 5-minute conventional Schirmer I test without anesthesia was performed on closed eyes. Tear BUT was measured and corneal fluorescein staining pattern evaluated in both groups. t test was used for comparison of the mean age of the two groups. Chi square test was used for the comparison of sex, smoking habits and tear function values of control and test groups. t test for was used for independent groups and chi square test was used for the comparisons. p:0.000 . Mean BUT was 13.8±14.5 in herpes group and 21.8±12.7mm p:0.009 . No statistically significant difference was found between two groups in terms of HSV-1IgG,M or HSV-2IgG,M positivity. The healthy eyes of the patients with herpetic stromal keratitis showed a decrease in tear secretion and tear film stability

Keywords:

Herpetic keratitis, contrlateral eye, tear function,

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