Treatment of Feline Mammary Fibroepithelial Hyperplasia with the Combination of Aglepristone and Cabergoline

Fibroepitelyal meme hiperplazi olgusu; kısırlaştırılmamış, 2 yaşlı, bir ay önce östrus göstermiş tekir dişi bir kedide aglepriston (Alizine, Virbac®) ve cabergolin (Galastop, Ceva®) kombinasyonu ile tedavi edildi. Tedavi günü, serum progesteron konsantrasyonu 2,96 ng/ml ve serum östradiol konsantrasyonu 5 pg/ml’den düşük olarak tespit edildi. Kedi, 15 mg/kg canlı ağırlığa (c.a.) aglepriston (Alizine, Virbac®) ile haftada iki gün üst üste 3 hafta boyunca ve bu tedaviye ek olarak cabergolin (Galastop, Ceva®) 5 μg/kg c.a. ile hergün günde 1 defa, per os (PO) birinci haftada uygulandı Üç hafta sonundaki muayenede, meme bezlerinde belirgin küçülme ve süt salgısının kesildiği saptandı. Tedavi başlangıcından 6 hafta sonra, meme bezlerinin tamamen küçüldüğü ve serum progesteron ve östradiol konsantrasyonlarının sırasıyla 0.142 ng/ml ve

KEDI MEME FIBROEPITELYAL HIPERPLAZISININ CABERGOLIN VE AGLEPRISTON KOMBINASYONU ILE TEDAVISI

A case of fibroepithelial mammary hyperplasia in a two years old, intact, tabby female cat that showed oestrus 1 month ago was treated with the combination of aglepristone (Alizine, Virbac®) and cabergoline (Galastop, Ceva®) administrations. On the day of treatment, serum progesterone concentration was detected as 2,96 ng/ml and serum oestradiol concentration was below 5,0 pg/ml. The cat was treated with subcutaneous (SC) injections of aglepristone (Alizine, Virbac®) 15 mg/kg body weight (b.w.) on two subsequent days per week for three weeks and 5 μg/kg b.w per a day, per os (PO) cabergoline (Galastop, Ceva®) administration was accompanied to this treatment on the first week for seven days. On the examination at the end of the third week, there was a marked regression of the mammary glands and the milk secretion ceased. Six weeks after the initiation of treatment, mammary glands were completely regressed and serum progesterone and oestradiol concentrations were 0.142 ng/ml, and

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