Aydın TÜRKMEN, Alaattin YILDIZ, Mehmet Şükrü SEVER, Mustafa ERTAŞ, Dilek KAYACAN, Barış BAŞLO, Seyit Mehmet KAYACAN

Kronik böbrek yetersizliğinde renal replasman tedavilerinin (diyaliz ve transplantasyon) üremik polinöropati üzerine etkilerinin karşılaştırılması

Amaç: Bu çalışmanın amacı kronik renal yetersizliği olan hastalarda diyaliz (dx) ve transplantasyonun (tx) üremik polinöropatiye etkinliklerinin karşılaştırılmasıdır. Gereç ve yöntem: Çalışmamıza 11 diyaliz (9'u hemodiyaliz, 2'si kronik periton diyalizli) ve 22 renal transplantlı olmak üzere toplam 33 hasta alındı. Kontrol grubunda 10 sağlıklı birey vardı. Renal replasman tedavisi yani dx veya tx yapılmadan önce ve tedavinin başlamasından 6 ay sonra elektrofizyolojik incelemeler yapıldı. Duysal iletiler olarak medyan, ulnar, radyal, sural ve superfisyel peroneal sinirlerde başlangıç (distal) latansı, tepe latansı, amplitüd, ileti hızı ve sural/radyal duysal cevap amplitüd oranı; motor iletiler olarak ise medyan, ulnar, peroneal ve tibial sinirlerde, distal latans, amplitüd ve ileti hızı hesaplandı. Ayrıca medyan ve tibial F dalga ile tibial H refleks latanslarıda incelendi.Bulgular: Duysal cevap başlangıç (distal) latansları ve tepe latanslarında (ms) dx hastalarında anlamlı bir değişiklik olmazken (örneğin, ulnar sinirde sırasıyla 2,05→2,0, p>0,5 ve 2,61→2,59, p>0,5; sural sinirde sırasıyla 2,95→2,96, p>0,5 ve 3,75→3,81, p>0,5), tx hastalarında anlamlı azalma saptandı (örneğin, ulnar sinirde sırasıyla 1,83→1,73, p

The comparision of the effectiveness of renal replacement therapies (dialysis and transplantation) on uremic polyneuropathy in chronic renal failure

Objective: The aim of this study was to compare the effectiveness of dialysis (dx) and transplantation (tx) on uremic polyneuropathy. Material and methods: Eleven dx and 22 tx recipients were included in this study. Also, there were ten healthy persons in the control group. Electrophysiologic studies were recorded before and after six months from the onset of dx and tx. Sensory parameters (distal latency, peak latency, amplitude, conduction velocity, and sural/radial amplitude ratio) were measured in median, ulnar, radial, sural and superficial peroneal nerves. Motor parameters (distal latency, amplitude, and conduction velocity) were recorded in the median, ulnar, common peroneal and tibial nerves. Additionaly, median and tibial F wave latency and tibial H latency were measured.Results: While sensory distal latencies and peak latencies (ms) did not change significantly in dx patients (2.05→2.0, p>0.5 and 2.61→2.59, p>0.5, in ulnar nerve, respectively; 2.95→2.96, p>0.5 ve 3.75→3.81, p>0.5, in sural nerve, respectively), there was a significant decrease in tx patients (1.83→1.73, p

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