Çıkım Ayşe SERTKAYA, Vakur AKKAYA, Neşe ÖZBEY, Yusuf ORHAN

Fazla kilolu ve şişman kadınlarda boy uzunluğunun risk göstergeleri ile ilişkisi

Amaç: Kısa boy bazı kardiyovasküler risk faktörleri ile ilişki göstermektedir. Bu çalışma fazla kilolu ve şişman kadınlarda boy uzunluğu ile çeşitli kardiyovasküler risk faktörleri arasındaki ilişkiyi araştırmak amacıyla gerçekleştirildi. Gereç ve yöntem: Beden kitle indeksi 25-67 kg/m2 arasında değişen 3665 fazla kilolu ve şişman kadında boy ile serum glukoz, ürik asit, total ve HDL-kolesterol, trigliserit, insülin, HOMA (homeostasis model assessment), sistolik ve diyastolik damar basıncı arasındaki ilişki, korelasyon analizi ve boy uzunluğuna göre ayrılmış dört grupta ANOVA, eşlenmemiş seri t-testi ve ki-kare testi ile araştırıldı. Bulgular: Olgularda boy uzunluğu ile ağırlık ve HDL kolesterol arasında anlamlı pozitif, boy uzunluğu ile yaş, beden kitle indeksi, glukoz, kolesterol, trigliserit, maksimum ve minimum damar basıncı ve bel-kalça oranı arasında anlamlı negatif ilişkiler bulundu. Boy ile ürik asit, insülin ve HOMA arasında anlamlı bir ilişki saptanmadı. Boy uzunluğuna göre dört gruba ayrılan olgularda ANOVA ile yaş, ağırlık, beden kitle indeksi, glukoz, maksimum ve minimum damar basıncı, kolesterol, trigliserit ve bel kalça oranı açısından gruplararası anlamlı farklar bulundu. Vakalarda çeyrek gruplar arasında diabetes mellitus, hipertansiyon, hiperkolesterolemi ve abdominal şişmanlık varlığı bakımından anlamlı farklılık bulundu. Aksine hipertrigliseridemi ve HDL-kolesterol düşüklüğü varlığı açısından anlamlı bir fark saptanmadı. Sonuç: Bulgularımız, fazla kilolu ve şişman kadınlarda kısa boyun hiperglisemi, hipertansiyon ve hiperkolesterolemi gibi tablolar birlikte olabileceğini desteklemektedir. Bu nedenle kısa boylu ve fazla kilolu veya şişman olan kadınlar kardiyovasküler risk varlığı bakımından daha yakından izlenmelidir.

The relationship between height measurement and metabolic risk markers in overweight and obese women

Objective: The aim of this study was to determine the relationship between height and cardiovascular risk markers in overweight and obese women. Materials and methods: The study group was composed of 3665 overweight or obese women with body mass index varying from 25 to 67 kg/m2. In order to determine the relationship between body height and various cardiovascular risk markers, ANOVA, unpaired-t test and chi-square tests were performed. Results: Data analyses indicated a significant positive relationship between height and weight and HDL cholesterol and an inverse relationship between height and age, serum total cholesterol, glucose, triglyceride, systolic and diastolic blood pressure. No significant relationship was found between height and uric acid, insulin and HOMA (homeostasis model assessment). Age, weight, body mass index, glucose, cholesterol, triglyceride, systolic and diastolic blood pressures were found to vary between quartiles of stature. The incidence of diabetes mellitus, hypertension, hypercholesterolemia and abdominal obesity also was found to differ significantly between quartiles of stature using ANOVA analysis. Conclusion: These results support the suggestion that short stature may be relevant to hyperglycemia, hypertension and hypercholesterolemia. Therefore, the measurement of metabolic risk markers could be useful in clinical screening for overweight and obese women of short stature.

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