Halkada siibstitiie olmug gegitli anilinlerin benzillenme ve benzoillenmeleri ilaq metabolizrna c;al~gmalannm substratlan ve muhtemel metabolitleri olarak gereksinilen benzil ve benzoil tiirevlerini elde etmek igin yapild~. Uygulanan ySntem ilgili amidlerle beraber arzu edilen sekonder '&linleri (ve ban durumlarda tersiyer aminleri) verdi. Bu maddelerin yapllan ve saflddan spektroskopik metodlarla onaylandi. Maddelerin baglanglq maddeleri ve kaq111kla1-1 olan primer anilinlerden aynlmalar~ ince tabaka kromatografisi ve kolon kromatografisi ile saglandi. Bu iiriinlerin bazilar~ bilinen bilegikler olmalanna ragmen, bu qal~gmada hedeflenen iiriinlerin elde edilmesinde kullamlabilecek bir aylrma teknigi he detayli spektroskopik ve kromatografik bulgular verilmektedir.  

The benzylation and benzoylation of certain ring substituted anilines were performed to produce benzyl and benzoyl derivatives which were required as substrates and potential metabolites for drug metabolism studies. The methods employed yieided the desired secondary anilines together with corresponding arnides. The structures and purity of these products were confirmed using spectroscopic methods and their separations from both starting rnateiials and conesponding primary anilines were achieved by use of column and thin-layer chromatography. Although some of these,products are known compounds, this present work decribes a useful separation technique and detailed spectroscopic and chromatographic data for the related required compounds under study.