FLAVONOIDS OF TANACETUM PRAETERITUM SUBSP. PRAETERITUM

A further investigatim on Tanacetum praeteritum subsp. praeteritumwhich is endemic in Turkey afforded five known flavonoids: apigenin, 6-hydroxyapigenin 6-methyl ether, luteolin, 6-methoxy luteolin and quercetagetin3,7-dimethyl ether (tomentin). Their structures were identified by UV, 'H NMR,EIMS and comparision on TLC with authentic compounds.This is the first report on the flavonoids of Tanacetum praeteritum subsp. praeteritum.Key Words: Conipositae,Tanacetum praeteritum subsp. praeteritum, flavonoids.

FLAVONOIDS OF TANACETUM PRAETERITUM SUBSP. PRAETERITUM

A further investigatim on Talzacetttnr praetel-itz~nz subsp. pl-aeter-itrlnr which is endemic in Turkey afforded five known flavonoids: apigenin, 6-hydroxyapigenin 6-methyl ether, luteolin, 6-methoxy luteolin and quercetagetiil 3,7-dimethyl ether (to~neqtin). Their structures were identified by UV, 'H NMR, EIMS and comparision on TLC with authentic compounds. This is the first report on the flavonoids of Tarzacetrtnl praeter-irrm~ subsp. praeteritunr.Tanacetrrm species are wide spread and important medicinal plants found throughout the world. Tanacetrlnz praeteritrlm subsp. praeteritrtnr which grows on rocks and limestone slopes 1200-2000 m is one of the endemic Tanacetun1 species in Turkey. In a previous work with this plant we have isolated 15 eudesmaolide type of sesquiterpene lactones [I]. In this study the author wishes to report the flavonoids of this species. The aerial part of Tanacetrfnl praeteritunt subsp. praeteritrrnz afforded the flavonoids: apigenin (1) [2], 6-hydroxyapigenin 6-methyl ether (2) [3], luteolin (3) [4], 6-hydroxy luteolin 6-methyl ether (4) [5], quercetagenin 3,7-dimethyl ether (tomentin) (5) [6]. 

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  • 1. Goren, N., Phytuchen~istly, 38,1261 (1995):
  • 2. Wollenweber, E., Phytuchenzistly, 13,753 (1974).
  • 3. Carman, N.T., Watson, T., Bierner, M.W., Averett, J., Sanderson, T., Seaman, S.C. and Marbry, T.J., Phytochentistly, 11,3271 (1977).
  • 4. Vandekerkhove, O.Z., Pflanzenphys., 86,275 (1978).
  • 5. Semro, G.E. and Coussio, J.C., Phyrocheniistly, 12,1825 (1973).
  • 6. Ulubelen, A., Kerr, M.K., Marbry, T.J., Phyrochenlistry, 19, 1761 (1980).