Pek qok saligmada sigara kullananlarm diisiik HDL-kolesterol diizeylerine sahip oldugu ve bunun koroner kalp hastahg~ (JXH) riskinin artmaslyla sonuslandigi gosterilmigtir. KKH'dan oliimler sigara i~enlerde ismeyedere oranla onernli derecede yiiksektir. Bu ~ahgmada 78 sa@kh ve 48 miokard infarktiisii.tarus~ konmug hastada serum lipid profilleri saptanrmg ve sigara kullarumm serum lipid profili da@- mina etkisi incelemigtir. Serum lipid diizeyleri enzimatik metodlarla tayin edilmi~tirSigara kullanan grupta HDL kolesterol duzeyleri sigara kullanmayan pba gore istatistiksel olarak anlamh derecede dugiik bulundu (p=0.007).

Several studies have shown that smoking lowers high density lipoprotein levels, resulting in an increased risk of coronary heart disease (CHD). Mortality from coronary heart disease is substantially higher in cigarette smokers thaq in nonsmokers. In this study, serum lipid profile was studied prospectively in healthy adults and in A group of patients with acute or old myocardial infarction. Serum lipid levels were measured enzymatically. Serum HDL cholesterol levels of smoking group was found lower than nonsmoking group with statistical significance (p=0.007).