Bahri OZER, Cihad TATAR, Husnu AYDİN, Mehmet Celal KİZİLKAYA, Suat BENEK, Ahmet KOCAKUSAK

The effect of demographic, biochemical and patholojical parameters on survival in colorectal cancer

Amac: Kolorektal karsinom en sık rastlanan malign tümörlerdendir. Bu çalışmada hastanemizde kolorektal kanser nedeniyle opere edilen hastaların verileri retrospektif olarak incelenerek elde edilen parametrelerin prognostik olup olmadıklarının araştırılması amaçlanmıştır. Gerec ve Yöntem: Kolorektal kanser nedeni ile ameliyat ettiğimiz 115 hasta değerlendirildi. Cinsiyet, yaş, tümör yerleşin yeri, lokal invazyon, 1.derece akrabada kanser öyküsü, kemoterapi alıp almadığı, histolojik grade, T evresi, tümör çapı, çıkarılan toplam lenf nodu sayısı, metastatik lenf nodu sayısı, pozitif lenf nodu oranı (PLNR) CEA, CA 19-9, albümin, CRP, takip sırasında sağ kalıp kalmadığı ve evreler kaydedildi.Hastalar takip sırasındaki hayatını kaybetme durumuna göre iki ayrı gruba ayrılarak parametreler kıyaslandı. Bulgular:BULGULAR: Gruplar arasında yaş ortalamaları, kırk yaş altı hasta oranları, cinsiyet oranları, aile öykülerinde, tümör yerleşim yerlerinde istatistiksel olarak anlamlı fark saptanmadı (sırasıyla p=0,411 p=0,545 p=0,656 p=0,659 p=0,177). Grup 2'de tümör özelliklerinden grade, T, metastatik lenf nodu sayısı, evre, PLNR ortalamaları, CEA, CA 19-9, CRP normal dışı sınır değer oranları Grup 1'e göre istatistiksel olarak anlamlı yüksek saptandı (CA 19-9 için p=0,034 diğer tüm karşılaştırmalar p

Kolorektal kanserde demografik, biyokimyasal ve patolojik parametrelerin sağkalıma etkisi

Aim: Colorectal cancer is one of the most commonly encountered malign tumors. In this study we studied the patients who have been operated for colorectal cancer retrospectively, to determine the parameters if they are prognostic or not. Materials and Methods: 115 patients who had been operated on because of CRC were evaluated. Gender, age, place of tumor, local invasion, cancer history in first-degree relatives, chemotherapy history, histological grade, T stage, tumor size, total number of resected lymph nodes, metastatic lymph node number, positive lymph node ratio (PLNR),CEA, CA 19-9, albumin, CRP, survival, stage of disease were recorded and those parameters were compared with each other in two groups according to survival during follow-up. Results: There were not any statistically difference as regard to age, young patients, gender, tumor location and family history between two groups ( p=0,411 p=0,545 p=0,656 p=0.177 p=0,659). However, statistically significant parameters in patients who died during follow-up were histological grade, T stage, the number of metastatic lymph node, stage, PLNR, CEA, CA 19-9 and CRP (p=0.034 for CA 19-9 and p

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