Fatih ERMİŞ, Mehmet Numan TAMER, Oğuzhan AKSU, Banu KALE KÖROĞLU, ismail Hakkı ERSOY, Selma KORKMAZ, İjlal ERTURAN

Prospective Case—Controlled Study of Endothelial Function in Patients with Mild to Moderate Psoriasis

Amaç: Bu çalışmanın amacı orta derecede psöriyazisi olan hastalarda endotelyel disfonksiyonu varlığınıinvaziv olmayan yöntemlerle araştırmaktır. Gereç ve yöntemler: Elli üç psöriyazisli hasta ve 53 sağlıklı birey çalışmaya dâhil edildi. Çalışmaya dahil edilen tüm hasta ve kontrol grubunun karotid arter intima--medya kalınlığı ve brakiyal arterin akım aracılı dilatasyonu ölçüldü. Bulgular: Çalışmaya dahil edilen tüm hastaların ortalama yaş, cinsiyet, vücut kitle indeksi, sigara alışkanlığı, antropometrik ölçümler ve arteryel kan basınçlarının hem psöriyazisli hasta hem de kontrol grubunda benzer olduğu görüldü. Hasta grubu değerlendirildiğinde ortalama psöriyazis alanı ve şiddet indeks skorunun 6.35:6.81 oldugu görüldü. Kontrol grubu ile karşılaştırıldığında hasta grubunda trigliserid seviyesi anlamlı olarak daha yüksekti (p

Hafif—Orta Psöriyazisli Hastalarda Endotel Fonksiyonlarının ProspektifVaka Kontrollü Değerlendirilmesi

Aim: The aim of this study is to investigate endothelial dysfunction in psoriasis patients with non-invasive methods. Materials and Methods: Fifty—three psoriasis patients and 53 healthy individuals were included in the study. Carotid artery intimae—media thickness and brachial artery flow-mediated dilation was measured both in patient and control groups. Results: Mean age, gender, body mass index, smoking habits, anthropometric measurements and arterial blood pressure values were similar in both groups. Mean psoriasis area and severity index score of psoriasis patients was 6.35:6.81. Triglyceride level was significantly higher (p

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