Ahmet ÖZTÜRK, Füsun ERDOĞAN, Ferhan SOYUER

İnme sonrası depresyon kognitif bozuklukla ilişkilidir

Amaç: İlk kez inme geçiren ve en az 3 ay hastalık süresi olan inme'li olgularda, depresyon ve kognitif fonksiyon arasındaki ilişkiyi karşılaştırmaktır. Metodlar: İnme sonrası 3. ayda, 70 hasta değerlendirmeye inmiştir.Olgularda, depresyon derecesi Beck Depresyon Değerlendirmesi (BDD), kognitif fonksiyon Mini Mental Durum Ölçeği (MMDÖ), fonksiyonel durum Fonksiyonel Bağımsızlık Ölçeği (FBÖ) ve inme şiddeti NIH ölçeği kullanılarak değerlendirilmiştir. BulgulanHastaların %8.6'da depresyon belirlenmiştir. Depresyon olan ve depresyon olmayan gruplar arasında, MMDÖ ve FBÖ değerlendirmeleri açısından istatistiksel olarak fark vardır (p

Poststroke depression correlates with cognitive impairment

Purpose: To compare the relation between depression and cognitive function in stroke cases having at least 3 months disease durationand first stroke . Methods:We evaluated 70 patients after the third months poststroke period. In these cases, in order to evaluate depression degree, Beck Depression Invantory (BDD), cognitive function Mini Mental State Examination (MMDÖ), functional situation Functional Independence Measurement (FBÖ) and stroke severity NIH measurement were used. Results: Depression was diagnosed in 8.6% of the patients at 3 months after the stroke. There was a statistically significant difference between the depressive and nondepressive groups in respect to the assessments of MMDÖ and FBÖ (p

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1.Williams LS, Gibose SS, Swindle RW. Depression and other mental health diagnoses increase mortality risk after ischemic stroke. Am J Psychiatry 2004; 161: 1090-5.
2.Sturm JW, Donnan GA, Dewey HM, Macdonell RA. Quality of life after stroke. The North East Melbourne Stroke Incidence Study. Stroke 2004; 35:2340-5.
3.Barba R, Martinez- Espinosa S, Rodriguez-Garcia E, Pondal M. Posttstroke dementiaxlinical features and risk factors. Stroke 2000; 31:1494-501.
4.Desmond DW, Moroney JT, Paik MC, Sano M. Frequency and clinical determinants of dementia after ischemic stroke. Neurology 2000; 54:1124-31.
5.Nys GMS, van Zardwort MJE, van der Worp HB. Early depressive symptoms after stroke: neuropsychological correlates and lesion characteristics.J Neurol Sci 2005; 228: 27-33.
6.Verdelho A, Henon H, Lebert F, Leys D. Depressive symptoms after stroke and relationship with dementia. Neurology 2004; 62:905-11.
7.Kauhanen M, Korpelainen JT, Hiltunen P. Poststroke depression correlates with cognitive impairment and neurological deficits. Stroke 1999; 30:1875-80.
8.Aben I, Denollet J, Lousberg R, Honig A. Personality and vulnerability to depression in stroke patients. Stroke 2002; 33:2391-95.
9.Güngen C, Ertan T, Eker E, Yaşar R, Engin F. Standardize Mini Mental Test'in Türk toplumunda hafif demans tanısında geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi 2002; 13:273-81.
10.Hisli N. Beck Depresyon Envanterinin Üniversite Öğrencileri için geçerliği, güvenirliği. Psikoloji Dergisi 1989;7(23):3-13.
11.Küçükdeveci AA, Yavuzer G, Elhan AH, Sonel B. Adaptation of the functional independence measure for use in Turkey. Clinical Rehabilitation 2001;15:311-9.
12.Brott T, Adams HP, Olinger CP ve ark. Measurements of acute cerebral infarction: aclinical examination scale. Stroke 1999; 20:864-70.
13.Aström M, Adolfsson R, Asplund K. Major depression in stroke patients. Stroke 1993; 24:976-82.
14.Burwill PW, Jouhnson GA, Chakera TM, Anderson CS. The place of site of lesion in the aetiology of poststroke depression. Cerebro Vase Dis 1996; 6:208-15.
15.Pohjasvaara T, Leppavuori A, Siira I, Kaste M. Frequency and clinical determinants of post stroke depression. Stroke 1998; 29:2311-7.
16.Robinson RG, Bolduc PL, Price TR A two year longitudinal study of poststroke mood disorders. Stroke 1987; 837-43.
17.Tatemichi TK, Desmond DW, Stern Y, Paik M. Cognitive impairment after stroke. J Neurol Neurosurg Psych 1994; 57:202-7.
18.Veiel HO. A preliminary profile of neuropsychological deficits associated with major depression. ] Clin Exp Neuropsychol 1997; 19:587-603.
19.Austin MP, Ross M, Murray C. Cognitive function in major depression. J Affect Disord 1992; 25:21-30.
20.Rasquin S, Lodder J, Verhey F. The association between psychiatric and cognitive symptoms after stroke. Cerebrovas Dis 2005; 19:309-16.
21.Nys GMS, van Zandvoort MJE, van de Worp HB. Early cognitive impairment predicts long-term depressive symptoms and a reduced quality of life after stroke. J Neurol Sci 2006; 247:149-56.
22.Parikh RM, Lipsey JR, Robinson RG. Two-year longitudinal study of post stroke mood disorders. Stroke 1987; 18:579-84.
23.Robinson RG, Bolla-Wilson K, Kaplan E. Depression influences intellectuel impairment in stroke patients. Br J Psychiatry 1986; 148: 541-7.
24.Feher EP, Mahurin RK, Doody RS, Cooke N. Establishing the limits of the Mini Mental State Examination of subtests. Arch Neurol 1992;49: 87-92.
25.Chemerinski E, Robinson R, Kosier JT. Improved recovery in activities of daily living in associated with remission of post stroke depression. Stroke 2001; 32:113-7.
26.Van de Weg FB, Kuik DJ. Poststroke depression and functional outcome. Clin Rehab 1999; 13:268-72.
27.Fruehwald S, Loffler H, Eher R. Relationship between depression, anxiety and quality of life. Psychopat 2001; 34:50-6.
28.Hosking S, Marsh N, Friedman P. Depression at 3 months poststroke in the elderly. Neuropsych&Cogn 2000; 7:205-16.
29.Kotila M, Numminen H, Waltimo O, Kaste M. Depression after stroke. Stroke 1998; 29:368-72.