Halime YILDIZ, Canan DEMİR, Tuğba GÜR, Şehriban YÜREKTÜRK, Arzu Esen TEKELİ

Van İlinin Merkez İlçelerinde Kuaför Çalışanlarında Bazı Antioksidan Enzim Düzeylerinin Belirlenmesi

Kuaförlük tehlikeli bir meslek olmasa da kuaförlerin alerjenler, kanserojenler veya organik solventler olarak bilinen kimyasal kombinasyonlara maruz kaldıkları bilinmektedir. Bu çalışmada, Van'daki kuaför çalışanlarında bazı önemli antioksidanlar olarak bilinen süperoksit dismutaz (SOD), katalaz (CAT) ve glutatyon (GSH) ile lipid peroksidasyonunun son ürünü ve oksidatif stres düzeyinin göstergesi olan malondialdehit (MDA) düzeylerinin belirlenmesi amaçlanmıştır. Araştırma kapsamına Van ili merkez ilçelerinde (Edremit, Tusba ve İpekyolu) çalışan 33 kadın kuaför çalışanı denek olarak, kuaför hizmetlerinden faydalanan gönüllü katılımcılar kontrol grubu olarak dahil edildi. Çalışmayı kabul edenlerden venöz kan alındı, laboratuvarda incelendi ve sonuçları istatistiksel olarak analiz edildi. MDA, CAT, SOD ve GSH için grup ortalamaları arasındaki fark istatistiksel olarak anlamlıydı (p<0.05). Sonuç olarak mesleki yaşamları uzun yıllar sürecek olan kuaförlerin, sürekli fiziksel ve kimyasal etkenlere maruz kaldıkları için egzama, astım, kalp-damar hastalıkları, kanser gibi reaktif oksijen türevlerinin de bulunduğu hastalıkların oluşumunda potansiyel risk grubunda olduğu söylenebilir.

Anahtar Kelimeler:

GSH, Katalaz, Kuaför çalışanları, MDA, SOD

DETERMİNATION OF SOME ANTIOXIDANT ENZYME LEVELS IN HAIRDRESSER EMPLOYESS IN THE CENTRAL DISTRICTS OF VAN PROVİNCE

Although hairdressing is not a dangerous profession, it is known that hairdressers are exposed to chemical combinations known as allergens, carcinogens or organic solvents. In this study, it was aimed to determine the levels of superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH), which are known as some important antioxidants, and malondialdehyde (MDA), the end product of lipid peroxidation and an indicator of oxidative stress, in hairdresser workers in Van. 33 female hairdresser employees working in the central districts of Van (Edremit, Tusba and Ipekyolu) were included in the scope of the study as subjects, and voluntary participants using hairdresser services were included as the control group. Venous blood was taken from those who accepted the study, examined in the laboratory, and the results were statistically analyzed. The difference between group means for MDA, CAT, SOD and GSH was statistically significant (p<0.05). As a result, it can be said that hairdressers, whose professional lives will last for many years, are in the potential risk group in the formation of diseases such as eczema, asthma, cardiovascular diseases, cancer, in which reactive oxygen derivatives also play a role, since they are constantly exposed to physical and chemical factors.

Keywords:

Catalase, GSH, Hairdresser workers, MDA, SOD,

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