KLİNİĞİMİZDE TANI KONULAN GÖZ VE ADNEKSLERİNİN PREMALİGN VE MALİGN LEZYONLARININ KLİNİK VE HİSTOPATOLOJİK ANALİZİ

Amacımız üçüncü basamak bir klinikte tanı konulan göz ve adnekslerinin premalign ve malign lezyonlarının klinikopatolojik analizini yapmaktır. Mart 2010 – Temmuz 2020 tarihleri arasında İnönü Üniversitesi Tıp Fakültesi Göz Hastalıkları Anabilim Dalı’nda ameliyat edilen ve patoloji laboratuvarına spesmen gönderilen hastaların dosyaları retrospektif olarak incelendi. Premalign ve malign lezyonu olan olguların demografik, klinik ve histopatolojik verileri kaydedildi. 64’ü kadın (%47.1), 72’si (%52.9) erkek toplam 136 hasta çalışmaya dahil edildi. Hastaların ortalama yaşı 73.6±14.7 (11-101) yıldı. 58 (%42.6) hastada premalign, 78 (%57.4) hastada malign lezyon tespit edildi. En sık rastlanan premalign lezyonlar konjonktival ya da korneal intraepitelyal neoplazi, karsinoma in situ iken, en sık rastlanan malign lezyonlar bazal hücreli karsinom, skuamöz hücreli karsinom ve lenfomaydı. Kliniğimizde en sık tanı konulan göz ve adnekslerinin premalign lezyonu konjonktival/korneal intraepitelyal neoplazi, malign lezyonu ise bazal hücreli karsinom olarak tespit edilmiştir.

Anahtar Kelimeler:

Bazal hücreli karsinom, Göz, Karsinoma in situ, Konjonktival intraepitelyal neoplazi, Skuamöz hücreli karsinom.

Clinical and Histopathological Analysis of Premalignant and Malignant Lesions of Eyes and Adnexes Diagnosed in Our Clinic

Our aim is to perform clinicopathological analysis of premalignant and malignant lesions of the eye and adnexa diagnosed in a tertiary clinic. The files of the patients who underwent surgery and sent specimens to pathology laboratory at Inönü University Faculty of Medicine, Department of Ophthalmology between March 2010 and July 2020 were reviewed retrospectively. Demographic, clinical and histopathological data of cases with premalignant and malignant lesions were recorded. A total of 136 patients, 64 (47.1%) female and 72 (52.9%) male, were included in the study. The mean age of the patients was 73.6±14.7 (11-101) years. Premalignant lesions were detected in 58 patients (42.6%) and malignant lesions were detected in 78 patients (57.4%). The most common premalignant lesions were conjunctival or corneal intraepithelial neoplasia, carcinoma in situ, while the most common malignant lesions were basal cell carcinoma, squamous cell carcinoma, and lymphoma. In our clinic, the most commonly diagnosed premalignant lesion of the eyes and adnexa was conjunctival intraepithelial neoplasia, and the malignant lesion was basal cell carcinoma.

Keywords:

Basal cell carcinoma, Carcinoma in situ, Conjunctival intraepithelial neoplasia, Eye, Squamous cell carcinoma.,

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