Prolaktin, Troid Stimülan Hormon ve Doğum Şeklinin Emzirme İle İlişkisi

Amaç: Normal doğum ve sezeryanla doğum yapan hastalarda emzirmede önemli olduğu bilinen PRL ve TSH düzeylerinin postpartum 2.saatteki değerlerinin karşılaştırılması. Materyal ve Metod: Sezeryan veya normal vajinal doğum yapmış postpartum 2. saatinde toplam 162 hasta çalışmamıza dahil edildi.Hastaların postpartum 2.saatindeki kan PRL ve TSH değerleri kaydedildi.Veriler Wann Whitney U test,Kruskal-Wallis test,NPar Testlerle değerlendirildi.Ayrıca sezeryanda anestezi tipi,BMI,gelir durumu, sigara, anne yaşı,travayda oksitosin kullanımı,bebek cinsiyeti ve bebek ağırlığının PRLve TSH hormonlarıyla ilişkisi değerlendirildi. Bulgular:162 hastanın 118'i normal vajinal doğum ve 44'ü sezeryan ile doğum yapmıştı.2 grup karşılaştırıldığında PRLP:0,016 değeri ile sezaryen grubunda normal doğum grubuna göre istatiksel olarak anlamlı yüksek tespit edildi. TSH için P değeri:0,439 ile iki grup arasında fark izlenmedi.Genel anestezi ve spinal anestezi grubunda PRLve TSH değerlerinde anlamlı fark bulunmadı.Diğer parametrelerinde hormon düzeylerini etkilemediği tespit edildi. Sonuç:Laktasyonda önemli olduğu bilinen prolaktin düzeyleri sezaryenden sonra anlamlı yüksek bulundu.Bu sonuç sezaryen ile doğumun laktasyonu olumsuz etkilediği görüşünü desteklememektedir..Sezeryan ile doğumdan sonra laktasyonun negatif etkilenmesi doğum şekline bağlı hormonal değişikliklere değil,eğitimle değiştirilebilen faktörlere bağlıdır.

Anahtar Kelimeler:

Hormon, Prolaktin, Beslenme, Dogum, Sezeryan

Breastfeeding Relationship Between Prolactin, Thyroid Stimulating Hormon Levels and Mode of Delivery

Introduction: The aim of this study was to compare Prolactine (PRL) and Thyroid stimulating hormone (TSH) levels, known to be important in lactation, at two hours postpartum between patients delivering vaginally and by cesarean operation. Material and Methods: Atotal of 162 patients delivering vaginally and by cesarean section were included in the present study. PRL and TSH values in the second hour postpartum were recorded and evaluated with the Mann–Whitney U test, Kruskal–Wallis test, and NPar test. In addition, the relationships between PRLand TSH hormone levels and the type of anesthesia administered during cesarean operation, Body mass index ( BMI) , income status, smoking history, age of mother, use of oxytocin in labor, weight of the infant, and sex of the infant were evaluated. Results: Of the 162 patients, 118 were delivered vaginally and 44 by cesarean section. Prolactin levels were significantly higher in cesarean section group when compared with normal vaginal delivery group (p=0.016). However, no significant difference was observed between two groups in terms of TSH levels (p=0.439). Similarly, no differences in PRL and TSH values were found between general anesthesia and spinal anesthesia groups. It was also established that other parameters did not affect hormone levels. Conclusions: Prolactin level, which is an important hormone during lactation, is found to be higher after cesarean section. This finding does not support the idea that lactation is diminished due to cesarean section. Negative impacts on lactation after cesarean section depend not on hormonal alterations related to mode of delivery, but on factors that can be modified through training and insight.

Keywords:

Hormone, Prolactin, Breastfeeding, Obstetric delivery, Cesarean section.,

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