Bebeklik döneminde formül mama ile beslenme alerjik rinit riskini arttırır mı?

Amaç:Bebeklik döneminde formül mama ile beslenmenin çocukluk çağında alerjik rinite yakalanma riskini arttırıp arttırmadığı retrospektif olarak araştırıldı.Materyal ve metod:Çalışmaya 01 Haziran 2018- 01 Eylül 2018 tarihleri arasında ikinci basamak bir hastanenin Kulak Burun Boğaz (KBB) polikliniklerine başvuran olan 876 hasta (355 (%40,5) erkek, 521 (59,5) kız, ortalama yaş: 10,1±5,7 ) dahil edildi. Hastalar alerjik rinit için skor (skor for allergic rhinitis; SFAR) anketi ile değerlendirildi. Fizik muayenenin alerjik rinit ile uyumlu olması ve SFAR ≥7 olması alerjik rinit lehine değerlendirildi. Bunun yanı sıra hastalara anne sütü ve yaşamın ilk iki yılında formül mama ile beslenme öyküleri soruldu. Hiç anne sütü ile beslenmemiş hastalar çalışma dışı bırakıldı. Yaşamın ilk iki yılında herhangi bir süre formül mama ile beslenme öyküsü olanlar formül mama (+), olmayanlar formül mama (-) olarak sınıflandırıldı.Bulgular:Çalışmamıza dahil edilen 876 hastanın 150 tanesine (%11,4) alerjik rinit tanısı konuldu. Alerjik rinit tanısı konulan hastaların %70 (n=105) i kız, %30 (n=45) u erkek cinsiyete sahip idi. Alerjik rinit kız cinsiyette anlamlı bir şekilde daha fazla idi (p=0,004). Yaşamın ilk iki yılında herhangi bir formül mama kullanım oranı %37,6 (n=329) idi. Ayrıca alerjik rinitli hastalarda formül mama ile beslenme oranı % 56 (n=84) iken, alerjik rinit olmayanlarda (-) hastalarda formül mama ile beslenme oranı %33,7 (n=245) idi. Alerjik rinit hastalarında formül mama ile beslenme oranı anlamlı bir şekilde daha fazla görüldü (p<0,001).Sonuç:Yaşamın ilk iki yılında herhangi bir formül mama ile beslenmek alerjik rinit riskini arttıran bir faktör olarak görülmektedir.

Anahtar Kelimeler:

Alerjik rinit, SFAR, formül mama ile beslenme

Does formula-feeding in infancy increase the risk of allergic rhinitis?

Background: It has been investigated whether feeding with formula in infancy increases the risk of allergic rhinitis in childhood.Methods: The study included a total of 876 patients 40.5% (n = 355) males, 59.5% (n =521) females with mean age 10,1±5,7 years, who applied to a secondary hospital Ear Nose and Throat (ENT) Clinic between June 01, 2018 and September 01, 2018. Patients were evaluated with ‘The Score for Allergic Rhinitis’ (SFAR) questionnaire. Consistency of physical examination with allergic rhinitis and the SFAR ≥7 were assessed in favor of allergic rhinitis. Besides this, patients were asked about their medical history if they had breast feeding and formula feeding in the first two years of life. Those who had a nursing history with formula in the first two years of life were grouped as Formula (+), and those without such a history were grouped as Formula (-).Results: Number of patient with allergic rhinitis were 150 (17.1%) in 876 patient who has been included in the study. Allergic rhinitis was significantly higher in female gender (p=0.004). The use rate of any formula-fed during infancy was 37.6% (n=329). While 56% (n=84) of allergic rhinitic patients had formula-fed history, 33,7% (n=245) of non-allergic rhinitic patients had formula-fed history. Allergic rhinitis was detected significantly higher in the ones who had formula-fed during their infancy period (p<0.001).Conclusion: Formula-feeding during infancy was seen as an increasing risk factor of allergic rhinitis.

Keywords:

Allergic rhinitis The score for allergic rhinitis, Formula-feeding, Microbiota,

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