Olgun Güven, Bahattin M. Baysal, Betül Taşdelen

Poli(N-izopropilakrilamid/itakonik asit) kopolimerik hidrojelleri tarafından sulu çözeltilerde vitamin $B_{12}$ adsorpsiyonu

Farklı miktarda itakonik asit içereb N-izopropilakrilamid/itakonik asit kopolimerik hidrojelleri (NIPAAm/IA) g-radyasyonu ile sentezlendi. Sentezlenen hidrojeller Vitamin $B_{12}$ tutulumu ve salımını incelemekte kullanıldı. Vitamin $B_{12}$ adsorpsiyon deneylerinde S tipi adsorpsiyon izotermi bulundu. Hidrojellerin ilaç tutulumu ve salımı davranışları üzerinde komonomer konsantrasyonu ve ışınlama dozunun etkileri araştırıldı.

Adsorption of vitamin $B_{12}$ in aqueous solutions by poly(N-isopropylacrylamide/ itaconic acid) copolymeric hydrogels

N-isopropylacrylamide/itaconic acid copolymeric hydrogels (NIPAAm/IA) containing different quantities of itaconic acid have been irradiated with γ radiation. The hydrogels were used in an experiment concerning the uptake and release behavior of Vitamin $B_{12}$. In the experiment of the adsorption of Vitamin $B_{12}$, type S adsorption isotherm was found. The effect of comonomer concentration and irradiation dose on the uptake and release behavior of the hydrogels was studied.

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