Burcu Tahire KÖKSAL, Özlem YILMAZ ÖZBEK, Esra ÖZMEN, Merih TEPEOĞLU

Stevens Johnson Sendromu Tanısı Alan Bir Çocuk Olgu

Stevens-Johnson sendromu (SJS) nadir görülen fakat hayatı tehdit edebilen mukokutanöz tutulumun olduğu T hücre aracılı bir aşırı duyarlılık reaksiyonudur. Olguların çoğu ilaçlarla tetiklenmektedir. Enfeksiyonlar, aşılar, kimyasallar, sistemik ve malign hastalıklar da etiyolojide rol alabilir. Hastalık genellikle ateş, halsizlik, başağrısı, miyalji, artralji ve üst solunum yolu enfeksiyonu gibi prodromal semptomlarla başlar. Stevens-Johnson sendromu için özel bir tedavi yöntemi bulunmamaktadır. Hastalık tanısının hızla konması, sebep olan ilacın erken dönemde kesilmesi ve destek tedavisi tedavinin temelini oluşturmaktadır. Sistemik steroid, intravenöz immünglobulin (IVIG) ve siklosporin gibi ilaçlar da tedavi amacıyla kullanılmaktadır. Stevens-Johnson sendromu farkındalığını arttırmak, erken tanı ve destek tedavinin önemini vurgulamak amacıyla SJS tanısı alan bir olgu sunulmuştur.ABSTRACT Stevens-Johnson syndrome (SJS) is a rare but life-threatening, mucocutaneous, T cell mediated hypersensitivity reaction. Most of the cases are triggered by a drug. Infections, vaccines, chemicals, systemic or malign diseases may have also roles in etiology. Disease generally starts with prodromal symptoms including fever, malaise, headache, myalgia or upper respiratory tract infection. There is no specific treatment modality for SJS. Diagnosing the disease rapidly, discontinuation of the suspected drug immediately, and supportive therapy are the main steps in treatment. Medications like systemic steroids, intravenous immunglobulin (IVIG) and cyclosporin are also used in treatment. Our aim in presenting a case of SJS is to increase awareness of this disease, to emphasize importance of immediate diagnosis and supportive therapy.

Anahtar Kelimeler:

Çocuk, IVIG, parasetamol, Stevens Johnson Sendromu

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