BÜLENT OĞUZ GENÇ, Savaş YAŞAR, EMİNE GENÇ, Orhan DEMİR, Mecit SÜERDEM

Kronik obstrüktif akciğer hastalıklılarda beyin sapı işitsel uyarılmış potansiyelleri

Amaç: Kronik obstrüktif akciğer hastalığında (KOAH) periferik sinir liflerinin etkilenebildiği bilinmektedir. Benzer şekilde santral işitsel yollarda etkilenmenin olup olmadığı araştırıldı. Yöntem: KOAH'ı bulunan 43 hastada (yaş ort.62.55 + 7.51) beyin sapı işitsel uyarılmış potansiyelleri (BAEP) kaydedildi. Bulgular: Periferik iletim zamanını gösteren I. dalga pik latanslarında kontrol grubuna göre anlamlı uzama olduğu görüldü, santral iletim zamanına ilişkin parametreler ise normal kontrol grubunda farklı bulunmadı. Sonuç: Bulgularımız kronik hipokside periferik sinirlerde gözlenen etkilenmenin santral sinir sistemine uzanmadığını düşündürmüştür.

Anahtar Kelimeler:

Merkezi sinir sistemi, Uyarılma potansiyelleri, işitsel, beyin sapı, Akciğer hastalığı, kronik obstrüktif, Oksijen azlığı, beyin, Sigara içme

Brainstem auditory evoked potentials in chronic obstructive pulmonary disease

Objective: Peripheral nerve involvement has been evidenced by a large number of nerve conduction studies in patients with chronic obstructive pulmonary disease (COPD). We evaluated whether a similar involvement exists in central auditory pathways in these patients. Method: we recorded the brainstem auditory evoked potentials (BAEP) in forty three subjects with COPD of mean age 62.55 + 7,51. Results: Peak latencies of wave I were found to be significantly prolonged in COPD patients while parameters of central transmission time showed no significant difference from those of the controls. Conclusion: Our results seem to suggest that central nervous system remains unaffected by chronic hypoxia.

Keywords:

Central Nervous System, Evoked Potentials, Auditory, Brain Stem, Pulmonary Disease, Chronic Obstructive, Hypoxia, Brain, Smoking,

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