Endobronchial tuberculosis mimicking lymphoma
Endobronşial tuberküloz farklı klinik tablolarda karşımıza çıkabilir. Biz bu yazıda öksürük şikayeti olan 55 yaşındaki bir kadın hastayı sunduk. Hastanın palpe edilebilen supraklaviküler ve servikal lenf nodları mevcuttu. Toraks BT’de multipl konglomere mediastinal lenf nodları mevcuttu. Fiberoptik bronkoskopik incelemede ise yaygın mukozadan kabarık mukozal nodülariteler her iki akciğer alanlarında tespit edildi. Bronş lavajı ARB’si negatif olmasına rağmen endobronşial alandan alınan biyopsiler tüberküloza uyan şekilde kazeöz granulomatöz inflamasyonla uyumluydu. Tüberküloz tedavisi başlandıktan bir ay sonra düzelme tespit edildi. Bu olgu sunumu özellikle tüberküloz insidansının yüksek olduğu populasyonlarda multipl mediastinal lenfadenopatilerin ayırıcı tanısında fiberoptik bronkoskopinin önemini göstermektedir.
Lenfomayı taklit eden endobronşial tüberküloz
Endobronchial tuberculosis may present with different clinical pictures. We presented a 55 year old patient with complaint of cough. She had palpable supraclavicular and cervical lymph nodes. Thorax CT revealed multiple conglomerated mediastinal lymph nodes. Multiple swollen mucosal nodularities were observed on bilateral endobronchial area during fiberoptic bronchoscopy. Although acidfast bacilli were negative in bronchial lavage fluid, biopsies obtained from the endobronchial nodules revealed caseous granulomatous inflammation compatible with tuberculosis. Improvement was achieved one month following antituberculosis therapy. This case report shows the importance of fiberoptic bronchoscopy in the differential diagnosis of subjects present with multiple mediastinal lymphadenopathies especially in populations where incidence of tuberculosis is high.
___
- 1. Matthews JI, Matarese SL, Carpenter JL. Endobronchial tuberculosis simulating lung cancer. Chest 1984;86(4):642-4.
- 2. Lee YH, Sin Fai Lam KN. Endobronchial tuberculosis simulating bronchial asthma. Singapore Med J 2004;45(8):390-2.
- 3. Lee JH, Park SS, Lee DH, Shin DH, Yang SC, Yoo BM. Endobronchial tuberculosis. Clinical and bronchoscopic features in 121 cases. Chest 1992;102(4):990-4.
- 4. Yanardag H, Tetikkurt C, Tetikkurt S, Demirci S, Karayel T. Computed tomography and bronchoscopy in endobronchial tuberculosis. Can Respir J 2003;10(8):445-8.
- 5. Kim HC, Kim HS, Lee SJ, Jeong YY, Jeon KN, Lee JD, et al. Endobronchial tuberculosis presenting as right middle lobe syndrome: Clinical characteristics and bronchoscopic findings in 22 cases. Yonsei Med J 2008;49(4):615-9.
- 6. Chan HS, Sun A, Hoheisel GB. Endobronchial tuberculosis-is corticosteroid treatment useful? A report of 8 cases and review of the literature. Postgrad Med J 1990;66(780):822-6.
- 7. Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest 2005;128(4):2893-909.
- 8. Chung HS, Lee JH. Bronchoscopic assessment of the evolution of endobronchial tuberculosis. Chest 2000;117(2):385-92.
- 9. Kurasawa T, Kuze F, Kawai M, Amitani R, Murayama T, Tanaka E, et al. Diagnosis and management of endobronchial tuberculosis. Intern Med 1992;31(5):593-8.
- 10. Kim YH, Kim HT, Lee KS, Uh ST, Cung YT, Park CS. Serial fiberoptic bronchoscopic observations of endobronchial tuberculosis before and early after antituberculosis chemotherapy. Chest 1993;103(3):673-7.
- 11. Caglayan S, Coteli I, Acar U, Erkin S. Endobronchial tuberculosis simulating foreign body aspiration. Chest 1989;95(5):1164.