Onur DEDE, Süleyman YEŞİL, Gülay DEDE, İsmail NALBANT, Kürşad ZENGİN, Muhammed Abdurrahim İMAMOĞLU

The long-term effect of uretral dilatation therapy combined with steroid after ınternal urethrotomy

Amaç: Primer üretral darlıklarda hidrofilik dilatasyon kateteri ve steroid emdirilmiş hidrofilik dilatasyon kateteri kullanımının uzun dönem sonuçlarını göstermek amaçlandı. Yöntemler: Primer üretral darlık tanısı 1.5 cmden küçük olan komorbiditesi olmayan 41 erkek hasta çalışmaya dahil edildi. İnternal üretrotomi uygulamasından sonra hastalar iki grup halinde randomize edildi. Grup 1e steroid emdirilmiş (triamcinolone acetonide (%1) 18F hidrofilik kateter 2 hafta süre ile uygulandı, grup 2ye 18F hidrofilik kateter 2 hafta süre ile uygulandı ve ameliyat sonrası 3. gün hastaların sondaları çekildi. Ameliyat sonrası takiplerde üroflowmetri ve tekrarlama oranları kullanıldı. Bulgular: Ortalama hasta yaşları sırasıyla 45.1±8.0 ve 47±8.8 (68-29) yıl idi. Üretral darlık uzunluğu grup 1 için 7.4±4.0 mm, grup 2 için 7.8±4.3 mm idi( p=0.79). Bütün hastaların üroflowmetri oranları (Q max) 6, 12, 24 ve 36. aylarda ölçülerek değerlendirildi. Grup 1de 3 (%13) ve grup 2de 3 (%15) hastada üretral darlığın tekrarı izlendi ve bu istatistiksel olarak anlamlı bulundu. Sonuç: Ek tedavi olarak bu metod zahmetsiz, düşük komplikasyonlu, ve ümit vericidir. Şu an için bu metodun etkinliğinin objektif değerlendirilmesi için daha geniş sayıda hasta grubuna ihtiyaç vardır.

İnternal üretratomi sonrası steroid ile kombine edilmiş üretral dilatasyon tedavisinin uzun dönem etkisi

Objective: To present the long-term results of hydrophilic dilatation catheter or steroid-coated hydrophilic dilatation catheter usage in the management of primary urethral stricture. Methods: Forty-one male patients with a diagnosis of primary urethral stricture shorter than 1.5 cm and no comorbities were included in this study. After application of internal uretrotomy, these patients were randomized into two groups. A steroid-coated (triamcinolone acetonide (1%) 18F hydrophilic dilatation catheter was applied to the patients in group 1 for 2 weeks and an 18F hydrophilic dilatation catheter was applied to the patients in group 2 for 2 weeks, and catheters were removed after 3 days. Uroflowmetry and recurrence rate was used in postoperative follow-ups. Results: Mean patient age were respectively 45.1±8.0 and 47±8.8(68-29) years. Urethral stricture length was evaluated for group 1 7.4±4.0 mm and group 2 7.8±4.3 mm p:0.79. All patients uroflowmetry value (Q max) were followed up on 6,12,24 and 36 month and results were evaluated. Recurrence of urethral stricture was determined in 3 (13%) patients in group 1, and 3 (15%) patients in group 2 (p

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