Sağlıklı Erkeklerde Sigara İçiminin Eritrosit Parametreleri ve Glukoz Düzeyine olan Etkisi

Amaç: Sigara kullanımı ve paket/yıl değerlerinin kırmızı kan hücresi sayılarına ve buna bağlı parametrelere, ayrıca glukoz konsantrasyonuna olan etkisini değerlendirmektir. Yöntem: Otuz kontrol (sigara içmeyen) ve 30 (sigara içen) olmak üzere toplam 60 hasta dahil edildi. Sigara içenler, paket/yıl değerine göre iki gruba ayrıldı. Kırmızı kan hücresi parametreleri ve glukoz düzeyi sigara içen ve sigara içmeyen kişilerde analiz edildi. Sigara içenlerin karşılaştırılmasında bağımsız T-testi, sigara içme gruplarının karşılaştırılması için tek yönlü ANOVA kullanıldı. Bulgular: Bu çalışmada sigara içenler arasında kırmızı kan hücresi parametreleri ve glukoz düzeyleri açısından anlamlı bir değişiklik görülmedi. Elde edilen sonuçlar sigara kullanım süresine bağlı olarak; kırmızı küre sayısı (RBC), hemoglobin düzeyi (HGB), hematocrit yüzdesi (HCT) ve ortalama eritrosit hemoglobin konsantrasyonu (MCHC) açısından farklılık gösterirken; ortalama eritrosit birim hacimi (MCV), ortalama eritrosit hemoglobin miktarı (MCH) ve kırmızı küre dağılım genişliği (RDW) ve glukoz düzey, açısından farklılık saptanmamıştır. Sonuç:Bu çalışma, sigara kullanımının sağlıklı kişiler üzerinde RBC sayıları ve buna bağlı parametreler ile glukoz seviyesi üzerine istatistiksel olarak etkisi olmadığını ortaya koymuştur. Bununla birlikte, sigara içme süresinin istatistiksel olarak RBC, HGB, HCT ve MCHC üzerinde etkili olduğu halde MCV, MCH, RDW ve glukoz düzeyini etkilemediği saptanmıştır.

Effect of Pack-Year of Cigarette Smoking on Erythrocyte Parameters and Glucose Level Among

Objective: To evaluate the effect of cigarette smoking and pack-year of cigarette smoking on red blood cell counts and its related parameters, also glucose concentration. Methods: Sixty consenting subjects of which 30 controls (non-smokers) and 30 cases (smokers) were studied. Smokers were divided into two groups based on pack-year of cigarettes smoked. The red blood cell parameters and glucose level were analyzed in smoker and non-smoker. Independent T-test was used to comparison of a smoker and also one way ANOVA was used to comparison packyear of smoking groups. Results: The present study showed no changes significantly in red blood cell parameter and glucose level between in smoker. The current result appeared alteration of red blood cells counts (RBC), hemoglobin level (HGB), hematocrit percent (HCT) and mean corpuscular hemoglobin concentration level (MCHC), while no difference of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW) and glucose level in duration of smoking. Conclusions: This study revealed that cigarette smoking statistically no effect on RBC counts and its related parameters and glucose level among healthy. However, the duration of smoking statistically had the effect on RBC, HGB, HCT and MCHC while had no effect on MCV, MCH, RDW and glucose level.

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