Migren Kliniğinde Optometrik Bulguların Önemi
Giriş: Migren, saatler ya da günler sürebilen, zonklayıcı karakterli, bulantı,kusma, ışık ve ses hassasiyetinin eşlik ettiği bir baş ağrısıdır. Migren ile kırmakusurları ve binoküler görme anomalileri arasında bir ilişki bulunduğuna dairiddialar bulunmaktadır. Bu çalışmada, migren tanısı almış hastalardaoptometrik ve ortoptik bulguları incelemeyi ve sağlıklı bireylerle kıyaslamayıamaçladık.Yöntem: Çalışmamıza, 58 migren hastası ve 50 sağlıklı kontrol dahil edildi.Hastalar, astenopik şikayetler, fotofobi ve görsel semptomlar açısındansorgulandı. Hastaların; sferik kırma kusuru, astigmatik kırma kusuru, sferikeşdeğer, düzeltilmiş en iyi görme keskinliği, ön segment ve fundus muayenesi,motilite muayenesi, füzyon aralıkları ve stereopsis ölçümleri kaydedildi.Bulgular: Migren hastalarında miyopik ve astigmatizmatik kırma kusuru dahafazla izlendi, yakın füzyonel konverjans amplütüdleri ise daha düşük izlendi(sırasıyla p=0.020, p=0.019, p=0.00).Sonuç: Kırma kusuru varlığı ve füzyon mekanizmalarının yetersizliği migrenkliniğine olumsuz katkı sağlıyor olabilir. Bu nedenle, migren hastalarınauygulanacak düzenli göz muayeneleri ile mevcut kırma kusurları ve ortoptikanomaliler saptanmalı ve tedavi edilmelidir.
The Optometric Correlates of Migraine
Objective: Migraine is one of the most common debilitating diseases characterized by pulsating headaches continued from a few hours to several days, accompanied by nausea, vomiting, sensitivity to light and sound. There have been claims of a relationship between migraine headaches and refractive errors and binocular vision anomalies. In this study, we aimed to evaluate optometric and ortoptic findings in patients with migraine headache and to compare with healthy subjects. Methods: This study includes 58 patients with migraine and 50 healthy subjects. Asthenopic symptoms, fotofobia, and visual symptoms of the patients were noted. Detailed ophthalmological examinations were performed containing spherical refractive error, astigmatic refractive error, spherical equivalent (SE), best-corrected visual acuity, slit lamp biomicroscopy, fundus examination. Also, ortoptic examination was performed icluding ocular motility, fusional reserves, and stereopis measurements. Results: Myopia and astigmatism were more frequent in migraine patients and near fusional convergence amlitudes were lower when compared with the control subjects (p=0.020, p=0.019, p=0.00 respectively). Conclusion: This study suggests that refractive errors and insufficiency of fusional mechanisms may make a negative contribution to migraine headache. Therefore, people who experience migraine headaches should have opthalmological examinations regularly to ensure that their refractive errors and ortoptic abnormalities are appropriately managed.
___
- Headache Classification Sub-Committee of the International Headache
Society. The international classification of headache disorders. Cephalalgia
2004; 24: 1-160.
- Silberstein SD, Lipton BR, Goadsby PJ. Klinik Uygulamada Baş Ağrısı.
İstanbul: Yelkovan Yayıncılık, 2004: 69-128.
- Yücesan C. Migren ve Tedavisi. Türkiye Klinikleri J Neurol-Special Topics
2008; 1: 10-21.
- Arunagiri G, Shanmugam S. Migraine: an ophthalmologist’s perspective.
Curr Opin Ophthalmol 2003;14: 344-52.
- Shareef AH, Dafer RM, Jay WM. Neuro-ophthalmologic manifestations of
primary headache disorders. Semin Ophthalmol 2008; 23: 169-77.
- Harle DE, Evans BJ. The optometric correlates of migraine. Ophthal Physiol
Opt 2004; 24: 369–83.
- Shepherd AJ. Visual contrast processing in migraine. Cephalalgia 2000; 20:
865-80.
- Queiroz LP, Rapoport AM, Weeks RE, Sheftell FD, Siegel SE, Baskin SM.
Characteristics of migraine visual aura. Headache 1997; 37: 137–41.
- Shareef AH, Dafer RM, Jay WM. Neuro-ophthalmologic manifestations of
primary headache disorders. Semin Ophthalmol 2008; 23: 169-77.
- Drummond PD. A quantitative assessment of photophobia in migraine and
tension headache. Headache 1986; 26: 465–9.
- Drummond PD. Pupil diameter in migraine and tension headache. J Neurol
Neurosurg Psychiatry 1987; 50: 228–230.
- Drummond PD. Photophobia and autonomic responses to facial pain in
migraine. Brain 1997; 120: 1857–64.
- Gordon GE, Chronicle EP, Rolan P. Why do we still not know whether
refractive error causes headache? Towards a framework for evidence based
practice. Ophthal Physiol Opt 2001; 21: 45–50.
- Whittongton TD. The art of clinical refraction. London: Oxford University
Press, 1958; 11-8.
- Chronicle E, Mulleners W. Visual system dysfunction in migraine: a review
of clinical and psychophysical findings. Cephalalgia 1996; 16: 525–35.
- Gould GM. The history and etiology of migraine. JAMA 1904; 42: 168-72,
239-44.
- Snell S. Eye-strain as a cause of headache and other neuroses. London:
Simpkin Marshall, Hamilton, Kent & Co., 1904.
- Wilmut EB. Migraine. Br J Physiol Opt 1956; 13: 93–7.
- Akıncı A, Güven A, Değerliyurt A, Kibar E, Mutlu M, Çitirik M. The
correlation between headache and refractive errors. J AAPOS 2008; 12: 290-
3.
- Harle DE, Evans BJW. The correlation between migraine headache and
refractive errors. Optom Vis Sci 2006; 83: 82-7.
- Jenkins TCA, Pickwell LD, Yekta AA. Criteria for decompensation in
binocular vision. Ophthal Physiol Opt 1989; 9: 121–5.
- Yekta AA, Pickwell LD, Jenkins TCA. Binocular vision, age and symptoms.
Ophthal Physiol Opt 1989; 9: 115120.
- Evans BJW, Patel R, Wilkins AJ. Optometric function in visually sensitive
migraine before and after treatment with tinted spectacles. Ophthal Physiol
Opt 2002; 22: 130–42.
- Harle DE, Evans BJW. Subtle binocular vision anomalies in migraine.
Ophthal Physiol Opt 2006; 26: 587-96.