Ümit Özgür AKDEMİR, Fatma YILDIRIM, Murat TÜRK, Ahmet Selim YURDAKUL, Can ÖZTÜRK

Küçük Hücreli Dışı Akciğer Kanserinde Primer Tümör Metabolik Aktivitesi ile Lenf Nodu ve Uzak Organ Metastazı Arasındaki İlişki

Giriş: Çalışmamızda Küçük Hücreli Dışı Akciğer Kanseri (KHDAK) hastalarındatedavi öncesi çekilen pozitron emisyon bilgisayarlı tomografideki (PET-BT)primer kitlenin SUVmax olarak ölçülen 18F-FDG tutulumu (metabolik aktivitesi)ile lokal yayılım, lenf nodu metastazı ve uzak organ metastazı arasındaki ilişkiyiaraştırmayı amaçladık.Yöntem: Torasik onkoloji ünitemizde Mart 2009-Temmuz 2013 tarihleriarasında KHDAK tanısı alan, takip ve tedavi edilen 143 hastanın dosyasıretrospektif olarak incelendi. Hastaların demografik özellikleri, klinikevreleri,tedavi öncesi çekilen PET-BT’deki primer kitlenin SUVmax değeri, lokalyayılım olup olmadığı, lenf nodu ve uzak organ metastazları kaydedildi.Bulgular: Çalışmaya alınan 143 hastanın 37 (%25.8)’si erken (Evre I-II), 106(%74.2)’sı lokal-ileri (Evre III-IV) evre idi. Hastalar medyan SUVmax değeri13.0’e göre iki gruba ayrıldı. SUVmax ≥13 olan grupta 69 (%48.3) hasta,SUVmax

The Relationship Between Primary Tumor Metabolic Activity and Lymph Node and Distant Organ Metastasis in Non-Small Cell Lung Cancer

Objective: In our study we aimed to evaluate the relationship of SUVmax of 18FDG uptake (metabolic activity) of the primary tumor on the pretreatment PET-CT to local invasion, lymph node metastasis and distant organ metastasis in patients with non-small cell lung cancer (NSCLC). Method: Hospital records of 143 patients with NSCLC who were diagnosed, followed up and treated in our thoracic oncology department between March 2009-July 2013 were retrospectively analysed. Demographic features, clinical stages, SUVmax of the primary tumor on the pretreatment PET-CT, presence of local invasion, lymph node and distant metastasis of patients were recorded. Results: Out of the 143 patients, 37 (25.8%) were at early stage (stage 1-2), 106 (74.2%) were at local-advanced stage (stage 3-4). The patients were divided into two groups based on SUVmax according to median SUVmax of 13.0; 69 patients (48.3%) had a SUVmax≥13 and 74 (51.7%) had a SUVmax

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