Nesrin SEYHAN, Aysel ARICIOĞLU, Göknur GÜLER

Effects of electric fields on radical and antioxidant enzyme levels

Amaç: Günümüzde çevrenin kimyasal maddelerle kirletilmesi yoğun eleştirilere neden olurken; elektromagnetik çevre kirlenmesi gündemimize yeni girmeye başlamış konulardandır. Teknolofinin gelişimi ile elektromagnetik enerjinin kullanımının giderek yaygınlaşması nedeniyle çoğumuz sürekli olarak değişik şiddet, süre ve doğrultularda elektrik alanlara daha çok maruz kalmaktayız. Elektrik alanların sağlığımız üzerindeki etkilerini araştırmak amacıyla çok sayıda çalışma yapılmakta ve bu araştırmalar gün geçtikçe artmaktadır. Bu çalışmada farklı şiddet ve doğrultularda uygulanan elektrik alanların dalak ve testis dokularında lipid peroksidasyon ve antioksidan enzimler üzerindeki etkileri kobaylarda incelendi. Metod: Tahta kafesler üzerine monte edilmiş olan bakır plakalara potansiyel fark uygulanarak 1.8, 0İ9 ve 0.3 kV/m şiddetinde elektrik alanlar oluşturuldu. Her grupta 10 adet kobay olmak üzere toplam 60 adet erkek beyaz kobay günde 8 saat olmak üzere 3 gün boyunca elektrik alanlara sürekli olarak maruz bırakıldı. Elektrik alan uygulama işlemine saat 9.00'da başlanıp 17.00'de son verildi. On adet kobay ise kontrol grubunu oluşturdu. Farklı şiddet ve doğrultularda uygulanan elektrik alanların malondialdehit (MDA) ve superoksit dismutaz (SOD) seviyelerine etkisi araştırıldı. Sonuç: Dalak ve testis dokularında, uygulanan elektrik alanın şiddeti arttıkça MDA ve SOD seviyelerinde artış tespit edilmiştir. Tartışma: Günlük yaşamda farkına varmadan maruz kaldığımız şiddet ve doğrultulardaki elektrik alanlardan vücudumuzdaki radikal sentezinin etkilenebileceğini söyleyebiliriz.

Radikal ve antioksidan enzim seviyesine elektrik alanların etkisi

Purpose: Today environmental pollution by chemical substances is intensely criticized; however, electromagnetic pollution of the environment has only started to be discussed recently. Due to the development of technology and the increased use of electromagnetic energy, most of us are exposed to electric fields at different intensities, exposure periods and directions. Much research has been performed to investigate the effects of electric fields on our health and the number of these studies is increasing. The aim of this study is to determine lipid peroxidation and SOD levels ih spleen and testis tissues exposed to different intensities and directions of electric fields. Methods: Electric potentials were applied to copper plates mounted on wooden boxes to produce electric fields with magnitudes of 1.8, 0.9 and 0.3 W/m. Male white guinea pigs were continuously exposed to electric fields for 8 hours per day over 3 days. A total of 60 guinea pigs were exposed to electric fields. Each group of 10 guinea pigs was exposed from 9 a.m. to 5 p.m. Ten guinea pigs were used as controls. The effect of electric field exposure on malondialdehyde (MDA) and superoxide dismutase (SOD) levels was investigated for different intensities and directions. Results: Increasing the intensity of the electric fields caused an increase in the MDA and SOD levels detected in spleen and testis tissues. Conclusion: Electric fields, which we are exposed to without our being aware of it in our daily lives, may have an effect on the radical synthesis in our bodies.

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