Celalettin ÇETİN, Kemal DAĞALP, Mehmet BAYSALLAR, Yüksel ATEŞ, Sadi SOYSAL, Mustafa GÜLŞEN, Sait BAĞCI, Abdullah KILIÇ

Characteristics of biliary bacterial colonization and bacteremia following endoscopic retrograde cholangiopancreatography

Amaç: Biliyer enfeksiyonlar ve septisemi, ERCP ve sfinkterotominin olası komplikasyonlarından olup bu işlemlerin faydalarını riske atarlar. Bu çalışmanın amacı, belirli bir dönemde, ERCP sonrası enfeksiyöz komplikasyonlara hangi tip hastaların daha yatkın olduğunu, rol oynayan patojen etkenleri ve bunlar için en uygun antibiyotikleri araştırmaktı. Yöntem: 37 hastanın (21 kadın, 16 erkek, yaş ortalaması 54) kan (ERCP'den once ve hemen sonra) ve safra örnekleri (ERCP sırasında) alınıp aerobik ve anaerobik bakteriler için kültürlere ekildi. Belirlenen patojenler, elde edilen antibiogramlar, endoskopik işlem ve son tanı ile enfeksiyöz komplikasyonun ilişkisi gözden geçirildi. Bulgular: 28 (%76) hastada biliyer enfeksiyon gözlendi. Belirlenen mikroorganizmaların çoğunluğu Gram negatif basillerdi. Biliyer enfeksiyonlar, terapötik ERCP hastalarında (n: 24), diagnostik ERCP hastalarına (n: 13) oranla daha sık görüldü (p

Endoskopik retrograd kolanjiopankreatografiyi takip eden biliyer bakteriyel kolonizasyon bakteriyeminin özellikleri

Purpose: Biliary infection and septicemia are probable fatal complications of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy that may compromise their benefits. The aim of this study was to investigate which patients are more susceptible to the infectious complications following ERCP in a specific era, and to identify the type of pathogens involved and the appropriate antibiotics for these microorganisms. Methods: Bile (during ERCP) and blood samples (before and right after ERCP) were obtained in 37 patients (21 females,16 males, mean age 54) and cultured for aerobic and anaerobic bacteria. The pathogens identified, the antibiograms obtained, and the relationship of the type of endoscopic procedure and the final diagnosis with the type of infectious complication were evaluated. Results: Biliary bacterial colonization was observed in 28 (76%) patients. The majority of the identified microorganisms were Gram-negative bacilli. Biliary bacterial colonization were seen more frequently in therapeutic ERCP patients (n: 24) than in diagnostic ERCP patients (n: 13) (p

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