Bir çocuk olguda ebv enfeksiyonuna bağlı gelişen akut kolesistit

Ebstein-Barr virüs (EBV) Herpes-viridae ailesinin bir üyesidir. EBV enfeksiyonu seyrinde karaciğer enzimlerinde yükselme sıklıkla izlenmekle birlikte akut kolesistit nadir görülmektedir. Burada 11 yaşında EBV enfeksiyonuna bağlı gelişen akut kolestatik hepatit ve akut kolesistit olgusu sunulmuştur. Hasta semptomatik tedavi ile cerrahiye gerek kalmaksızın düzelmiştir. Hekimler EBVye bağlı gelişen enfeksiyoz mononükleoz seyri sırasında asemptomatik transaminazemi dışında, kolestatik hepatit ve kolesistit gelişebileceğini, klinik iyileşmeye paralel olarak bu komplikasyonların düzeleceğini akılda bulundurmalıdır.

Ebv associated acute cholecystitis in a child

Ebstein-Barr virus (EBV) is a member of Herpes-viridae. Altough elevations of liver enzymes is commonly seen during the EBV infection, acute cholecystitis is rare complication. Herein, we report cholestatic hepatitis and acute cholecystitis associated with EBV infection in an 11-year-old boy. The patient recovered with symptomatic treatment without surgery. Physicians should keep in mind that cholestatic hepatitis and cholecystitis may develop during the course of EBV-induced infectious mononucleosis and these complications will recover in parallel with clinical improvement of primary disease.

___

  • 1.Vouloumanou EK, Rafailidis PI, Falagas ME. Current diagnosis and management of infectious mononucleosis. Curr Opin Hematol 2012; 19: 14- 20.
  • 2. Lennon P, Saunders J, Fenton JE. A longer stay for the kissing disease: epidemiology of bacterial tonsillitis and infectious mononucleosis over a 20- year period. J Laryngol Otol 2013; 7: 1-5.
  • 3. Gupta E, Bhatia V, Choudhary A, Rastogi A, Gupta NL. Epstein-Barr virus associated acute hepatitis with cross-reacting antibodies to other herpes viruses in immunocompetent patients: report of two cases. J Med Virol 2013; 85: 519-23.
  • 4. Kofteridis DP, Koulentaki M, Valachis A, Christofaki M, Mazokopakis E, Papazoglou G, et al. Epstein Barr virus hepatitis. Eur J Intern Med 2011; 22: 73-6.
  • 5. González Saldaña N, Monroy Colín VA, Piña Ruiz G, Juárez Olguín H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes 2012; 5: 361.
  • 6. Katz BZ. Epstein–Barr Virus (Mononucleosis and Lymphoproliferative Disorders). In: Long SS, Pickering LP, Prober CG, editors. Principles and Practice of Pediatric Infectious Diseases. 4th ed. Pennsylvania: Churchill Livingstone; 2012. p.1059-65.
  • 7. Chan CW, Chiang AK, Chan KH, Lau AS Epstein-Barr virus-associated infectious mononucleosis in Chinese children.Pediatr Infect Dis J 2003; 22: 974-8.
  • 8. Tahan V, Ozaras R, Uzunismail H, Mert A, Tabak F, Ozturk R, et al. Infectious mononucleosis presenting with severe cholestatic liver disease in the elderly. J Clin Gastroenterol 2001; 33: 88-9.
  • 9. Hinedi TB, Koff RS. Cholestatic hepatitis induced by Epstein-Barr virus infection in an adult. Dig Dis Sci 2003; 48: 539-41.
  • 10. Beltrame V, Andres A, Tona F, Sperti C. Epstein-Barr virus-associated acute acalculous cholecystitis in an adult. Am J Case Rep2012; 13: 153-6.
  • 11. Carrascosa MF, Caviedes JR, Soler-Dorda G, Saiz-Pérez C. Epstein-Barr virus acute cholecystitis. BMJ Case Rep. 2012. doi: 10.1136
  • 12. Iaria C, Arena L, Di Maio G, Fracassi MG, Leonardi MS, Famulari C, et al. Acute acalculous cholecystitis during the course of primary Epstein-Barr virus infection: a new case and a review of the literature. Int J Infect Dis 2008; 12: 391-5.
  • 13. Prassouli A, Panagiotou J, Vakaki M, Giannatou I, Atilakos A, Garoufi A, et al. Acute acalculous cholecystitis as the initial presentation of primary Epstein-Barr virus infection. J Pediatr Surg 2007; 42: 11-3.
  • 14. Yang HN, Hong KW, Lee JS, Eom JS. A case of acute cholecystitis without cholestasis caused by Epstein-Barr virus in a healthy young woman. Int J Infect Dis 2010; 14: 448-9.
Gazi Medical Journal-Cover
  • Yayın Aralığı: Yılda 4 Sayı
  • Yayıncı: Gazi Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Music therapy and hormonal responses in autism

Esra GÜNEY, Elvan İŞERİ, Banu ÇAYCI, Mehmet Fatih CEYLAN, Rahmi Oruç GÜVENÇ, Azize Andrea GÜVENÇ, Ersan ÇIRAK, Burak BAHAR, Şahnur ŞENER

Evaluation of clinical features of 238 cases with febrile convulsion

Yusuf AYDIN, Ebru YILMAZ, Deniz YILMAZ, Mesut KOÇAK, Ali Osman KÖKSAL, Osman ÖZDEMİR, Aslıhan YILMAZ ARASLI

A metastatic parachordoma case

Ajlan ATASOY, Sener CİHAN, Birsen Songul CİHAN, Tugba Fahriye KOS, Nalan BABACAN AKGUL

Mother approaches to children with fever

Fatma Tuba YILDIRIM, Burcu ÖZKAN, Özgen HÜR, Mesut KOÇAK, Şanlıay ŞAHİN, Ali Osman KÖKSAL, Mehtap ACAR, Şerife YILMAZ, Osman ÖZDEMİR, Aslıhan YILMAZ ARASLI

Clinical speciality of 500 headache patients: Documentations of headache center

Levent E. İNAN, Serap ÜÇLER, Hilal TOGAN, Özlem COŞKUN

Asendan, arkus ve desendan aorta anevrizmasının hibrit tedavisi

G. Levent OKTAR, Abdullah ÖZER, M. Hakan ZOR, Hüseyin DEMİRTAŞ, Koray AKKAN

Bir çocuk olguda ebv enfeksiyonuna bağlı gelişen akut kolesistit

Gülsüm İclal BAYHAN, Çiğdem ÜNER, Muhammet Furkan BAKKAL, Gönül TANIR

Onbir yaşına kadar gözden kaçan siyanoz

Ayhan PEKTAŞ, Serdar KULA, Abdullah İrfan TAŞTEPE2, Fatma Sedef TUNAOĞLU, Ayşe Deniz OĞUZ, Semiha TERLEMEZ

Incidental situs inversus totalis detected by ga-68 dota-tate pet/ct

Emre DEMİRCİ, Metin HALAC, Sait SAGER, Sabire AKSOY YILMAZ, Sertac ASA

Laurance-moon-bardet-biedl sendromlu bir hastanın dental tedavisinde monitörize anestezi bakımı

Sıla ŞAHİN, Ayşe Hande ARPACI