A case of toxic methemoglobinemia following lidocaine application for circumcision

Toksik methemoglobinemi yaşamı tehdit edebilen bir durumdur. Genellikle lokal anesteziklerin kullanımına bağlı yan etki olarak gelişir. Erken tanı ve tedavi önemlidir. Bu yazıda, klinisyenlerin farkmdalığını artırmak amacıyla, sünnet için kullanılmış lidokaine bağlı gelişen methemoglobinemi olgusu sunulmaktadır. Olgu intravenöz metilen mavisiyle başarıyla tedavi edilmiştir.

Sünnet için kullanılan lidokain sonrası gelişmiş toksik methemoglobinemi

Toxic methemoglobinemia is a potentially life-threatening condition. It develops generally as a complication of the use of local anesthetics. Prompt recognition and quick institution of therapy is of utmost importance. In this paper, a case of methemoglobinemia that occurred after lidocaine application for circumcision is presented in order to increase awareness among clinicians about this condition. The case was treated successfully with intravenous methylene blue.

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  • 1-RehmanHU. Methemoglobinemia. West. J. Med. 2001;175:193-196.
  • 2-Percy MJ, Asian D. NADH-cytochrome b5 reductase in a Turkish family with recessive congenital methaemoglobinemia type l.J. Clin. Pathol. 2008; 61:1122-1123.
  • 3-Abu-laban RB, Zed PJ, Purssell RA, et al. Severe methemoglobinemia from topical anesthetic spray: case report, discussion and qualitative systematic review. CJEM. 2001 ;3:51-56.
  • 4-Saha SA, Kordouni MR, Siddiqui M, et al. Methemoglobinemia-induced cardio-respiratory failure secondary to topical anesthesia. Am. J. Therapeut. 2006;l 3:545-549.
  • 5-Jaffery Z, Ananthasubramaniam K. A rare side effect of transesophageal echocardiography: methemoglobinemia from topical benzocaine anesthesia. Eur. J. Echocardiogr. 2008;9:289-290.
  • 6-Gaigl Z, Seitz CS, Trautmann A. Methemoglobinemia due to local anesthesia with low-dose prilocaine. Dermatol. Surg. 2008;35:168-169.
  • 7-Raso SM, Fernandez JB, Beobide EA, et al. Methemoglobinemia and CHS Toxicity after topical application of EMLA to a 4-year-old girl with molhis-cum contagiosum. Pediatr. Dermatol. 2006;23:592-593.
  • 8-Wieringa JW, Ketel AG, van Houten MA. Coma in a child after treatment with the 'magic salve' lidocaine -prilocaine cream. Ned. Tijdschr. Geneeskd. 2006;150:1805-1807.
  • 9-Kwok S, Fischer JL, Rogers JD. Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report. J Med Case Reports. 2008;23;16.
  • 10-Neuhaeuser C, Weigand N, Schaaf H, et al. Postoperative methemoglobinemia following infiltrative lidocaine administration for combined anesthesia in pediatric craniofacial surgery. Paediatr Anaesth. 2008; 18:125-131.
  • 11-Percy MJ and Lappin TR. Recessive congenital methaemoglobinemia: cytochromeb5 reductase deficiency. Br. J. Haematol. 2008;141:298-308.
  • 12-Boran P, Tokuc G, Yegin Z. Methemoglobinemia due to application of prilocaine during circumcision and the effect of ascorbic acid. J. Pediatr. Urol. 2008;4:475-476.
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  • Yayın Aralığı: Yılda 4 Sayı
  • Yayıncı: Gazi Üniversitesi Tıp Fakültesi
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