Moderate versus high intensity exercise training on leptin and selected immune system response in obese subjects

Amaç: Obezitenin immün sistemi baskılamak suretiyle immün sistem üzerinde olumsuz sonuçları bulunmaktadır. Bu nedenle obez bireylerde infeksiyon ve bazı kanser türlerinin insidansında artış saptanmaktadır. Bu çalışmanın amacı obez bireylerde orta düzeyde ve yoğun egzersiz sonrası seçilmiş immün sistem ve leptin üzerine etkilerinin karşılaştırılması hedeflenmektedir. Metod: Yaşları 35 ile 55 arasında olan kırk obez erkek hasta çalışmaya dahil edildi ve bu hastalar iki eşit gruba ayrıldı. Birinci grupta bulunan hastalar (A) orta düzeyde aerobic egzersiz yaparken, ikinci gruptaki hastalar yoğun aerobik egzersizi 3 ay boyunca yaptılar. Bulgular: Grup A’daki hastalarda ortalama vücut kitle indeksinde (VKI) ve leptin seviyesinde sırasıyla %3.7 ve %9.2 azalma saptanırken ortalama immunglobulin G (Ig G) düzeylerinde %4.8 oranında bir artış tespit edildi. Buna karşılık grup B’deki hastalarda ortalama vücut kitle indeksinde ve leptin seviyesinde sırasıyla %3.4 ve %3.7 azalma saptanırken ortalama immunglobulin G (Ig G) düzeylerinde %2.3 oranında bir artış tespit edildi. Grup A ve B’deki hastalarda ortalama VKI ve leptin düzeyleri azalırken, IgG düzeyleri anlamlı oranda artış gösterdi. Sonuç: Bununla birlikte her iki grup arasında tedavi sonrasında anlamlı fark saptandı.

Obez bireylerde orta düzeyde ve ağır egzersizin leptin ve seçilmiş immün sistem üzerine etkileri

Aim: Obesity has adverse consequences on immune system, causing immunosuppression and thus, obese individuals have higher incidence of infections and certain types of cancer. The aim of this study was to compare changes in leptin and selected immune system response after moderate and intense aerobic exercise training in obese subjects. Method: Forty obese male subjects, their age ranged between 35 to 55 years old. The subjects were included into 2 equal groups; the first group (A) received moderate intensity aerobic exercise training. The second group (B) received high intensity aerobic exercise training for 3 months. Result: There was a 6.7% and 9.2% reduction in mean values of body mass index (BMI) and Leptin respectively and 4.8% increase in mean values of immunoglobulin G (IgG) in group (A). While , there was a 3.4% and 3.7% reduction in mean values of BMI and Leptin respectively and 2.3% increase in mean values of IgG in group (B) . The mean values of BMI and Leptin were decreased and IgG was increased significantly in group (A) and group (B).Also; there was a significant difference between both groups after treatment. Conclusion: Moderate intensity aerobic exercise training on treadmill is appropriate to improve BMI, leptin and IgG in obese male patients.

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