Hamdi GİRGİN, Nejat AYDIN, A. Demir YONGUÇ, Emine AKSOY, Remzi ÇORAK

Ve Şimdi Koyunların Viral Maedi-Visna 'sı Türkiye'de

1985 yılında Türkiye'de ilk kez dışalımla Batı Almanya'dan ,gelen koyunlarda maedi-visna teşhis edildi. Tanı, histopatolojik bulgulara ve serolojik yoklamalara dayandı. Olaylarımızda akciğerler boz - sarımtrak. boz-mavimtrak renkte ve her taraflarında düzenli kıvamda idiler. Akciğerler büyümüz ve normalden 2- 4 kat daha ağırdı; kesit yüzleri kuru idi. Histopatolojik değişiklikler Pneumonitis interstitialis chronica ile karakteristik idi ve alveoler aralıklar daralmış, bunların yerlerini kalınlaşan alveoler duvarlar almıştır. Mikroskobik incelemede kalınşamış alveol duvarları mazenşimal hücre proiferasyonu gösteriyordu; hücreler, bazıları makrofaj olan büyük, yuvarlar, mononükleer formlardan kısa fibroblastik hücrelere kadar değişiyordu. Alveoler kanalların düz kaslarında hipertrofi vardı. Perivasküler, peribronşiyal ve peribronşioler olarak lenfoid hücre proliferasyonu görüldü. Bronşçuklara yakın olarak alveolleri astarlayan hücrelerde epithelialization vardı. Bazı alveoler makrofajlar bir veya daha fazla, acayip,yuvarlak,intrasitoplasmik , 1-3 mikron çaplarında inkluzyonlar içeriyordu, 477 ve 2214 numaralı kan serum örnekleri AGIT'de maedi-visna antikorları için pozitif idiler.

Anahtar Kelimeler:

Maedi - Visna, maedi-visna, Koyun, Türkiye, 1985, 1987, Viral, Enfeksiyon, Hamdi GİRGİN, Nejat AYDIN, A. Demir YONGUÇ, Emine AKSOY, Remzi ÇORAK

And now viral maedi-visna in sheep is in Turkey

This being the first time, maedi-visna was diagnosed in the sheep imported from West Germany, in Turkey in 1985. The diagnosis was based on histopathological lesions and seralogical examination. In our cases, the lungs were of a uniformly grayish yellow to grayish blue color and of uniform consistency. Being distended the lungs appeared large; they weighed two to four times the normal; The cut supfaces were dry. Histopathological ·changes were characteristic of .a chronic interstitial pneumonia and the bulk of the alveolar space had been replaced by thickened al·veolar walls. In microscopic examination, thickened alveolar septa were showing mesenohymal cell proliferation; the cells varied from large round mononuclear forms. some of which appeared to be macrophages, to short fibroblastic cells. The smooth muscles of the alveolar ducts were hypertrophic. Perivascular. peribronchial and peribronchiolar lymphoid cell proliferation was seen. Near the bronchi, there was also some tendency for the alveolar lining cells to swell and become cuboidal. A few of the large macrophages were containing one or more peculiar. spherical, cytoplasmic inclusions from 1 to 3 microns in diameter. The two sera samples, 477 and 2214 were both positive on ager gel immunodiffusion test for maedi-visna- antibodies.

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