Abdullah GÜZEL, İbrahim Etem DURAL, Hayri DEMİRBAŞ

İNME GEÇİREN HASTALARDA OTONOMİK SİNİR SİTEMİNİN KALP HIZI TURBULANSI İLE DEĞERLENDİRİLMESİ

Giriş: Serebrovasküler hastalıklar sonrası genellikle otonomik disfonksiyon gelişmektedir. Otonomik disfonksiyonu gösteren testlerden biri de kalp hızı türbülansıdır. Bu çalışmada bizim amacımız kalp hızı türbülansı parametrelerini kullanarak akut iskemik inme sonrası otonomik disfonksiyonu değerlendirmektir. Yöntemler: Çalışmaya 30 akut iskemik inme ile hastaneye yatırılan hasta ve 15 sağlıklı birey dahil edildi. Hastaların yatışları esnasında çekilen bilgisayarlı tomografi ve manyetik rezonans görüntüleri incelendi. Sağ hemisfer, sol hemisfer ve beyin sapı- serebellum lezyonu olarak 3 sınıfa ayrıldı. Hastaların hastaneye yatışlarının ilk 24 saati içerisinde takılmış olan holter EKG(elektrokardiyografi) kayıtları incelendi. Kalp hızı türbülansı parametreleri olan türbülans başlangıcı (TB) ve türbülans eğimi (TE) kontrol grubu ile kıyaslandı. Bulgular: Çalışmaya alınan gruplar arasında cinsiyet, yaş, hipertansiyon, hiperlipidemi sigara kullanımı ve biyokimyasal parametreler açısından anlamlı bir farklılık yoktu. TB ve TE değerleri kontrol grubu ile kıyaslandığında anlamlı fark saptanmadı. (TB - 0.004970 (±0.02), -0.013627 (±0.01) p: 0.14, TE 6.81(±7.30), 7.67 (±5.30) p: 0.11). Sol hemisfer lezyonlu hastalarda TB ve TE için daha fazla anormal değer saptanmasına karşın istatistiksel fark saptanmadı. Sonuç: Akut inme ile kalp hızı türbülansı arasında ilişki gösterilememiştir.

Anahtar Kelimeler:

İNME, KALP HIZI TURBULANSI, OTONOMİK SİNİR SİSTEMİ

EVALUATION OF AUTONOMIC NERVOUS SYSTEM WITH HEART RATE TURBULENCE IN PATIENTS WITH STROKE

Introduction: Autonomic dysfunction usually develops after cerebrovascular diseases. Heart rate turbulence is one of the tests to show autonomic dysfunction. We aimed to evaluate autonomic dysfunction using heart rate turbulence parameters after acute ischemic stroke in this study. Methods: We included 30 patients hospitalized with acute ischemic stroke and 15 healthy individuals in the study. Computed tomography and magnetic resonance images taken during the hospitalization of the patients were examined. It was divided into 3 classes the right hemisphere, left hemisphere, and brainstem cerebellum lesions. Holter ECG(electrocardiography) records inserted within the first 24 hours of hospitalization of the patients were examined. Turbulence onset (TO) and turbulence slope (TS) parameters, which are heart rate turbulence parameters, were compared with the control group. Results: There was no significant difference between the groups included in the study in terms of gender, age, hypertension, hyperlipidemia smoking, and biochemical parameters. When TO and TS values were compared with the control group, no significant difference was found. (TO -0.004970 (± 0.02), -0.013627 (± 0.01) p: 0.14, TS 6.81 (± 7.30), 7.67 (± 5.30) p: 0.11). Although there were more abnormal values for TO and TS in patients with left hemisphere lesions, no statistical difference was found. Conclusion: No relationship has been shown between acute stroke and heart rate turbulence.

Keywords:

STROKE, HEART RATE TURBULENCE, AUTONOMİC NERVOUS SYSTEM,

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