Coryza Gangrenosa Bovum’un Baş-Göz Formu Belirlenen Sığırlarda Kan ve Beyin Omurilik Sıvısı Biyokimyası, Sitolojisi ve Hematolojik Parametrelerin Değerlendirilmesi

Bu çalışmada, coryza gangrenosa bovum’un (CGB) baş-göz formu belirlenen sığırların beyin omurilik sıvısı (BOS) ve kan serumlardaki biyokimyasal değişiklikler, hematolojik değişiklikler ve BOS'un sitolojik olarak incelenmesi amaçlanmıştır. Bu amaçla CGB’nin baş-göz formu belirlenen 22 adet sığır ve klinik olarak sağlıklı 10 adet sığırdan kan ve beyin omurilik sıvısı (BOS) alınmıştır. CGB grubunun kan serumlardaki AST, üre, glukoz, CK (P<0.05), LDH düzeyleri (P<0.01), ALT, ALP, kolesterol (P<0.05), Ca, total protein (P<0.01) ve Mg değerleri kontrol grubuna göre yüksek, albümin ve Fe düzeyleri (P<0.001) ise düşük bulunmuştur. CGB gurubundaki sığırların BOS'larında Ca (P<0.01) ve total protein düzeyleri (P<0.001) yüksek, glukoz düzeyleri (P<0.05) ise kontrol grubuna göre düşük olarak belirlenmiştir. Hematolojik bazı parametrelerde de gruplar arasında farklılık görülmüştür. CGB gurubundaki sığırların BOS'larında yapılan sitolojik incelemelerde, sitolojik lamlarda polimorfonükleer lökositler, lenfositler, eritrositler, mak- rofajlar ve plazma hücreleri belirlenmiştir.Sonuç olarakCGB’da, özellikle BOS'ta sitolojik ve biyokimyasal, ayrıca kanda biyokimyasal ve hematolojik sonuçları bir arada inceleyen sınırlı sayıda çalışma olduğundan, çalışmamızdan elde edilen sonuçların sığırların sinir sistemini etkileyebilenviral hastalıklarda gelecekte yapılacak çalışmalar için önemli bir veri oluşturabileceği düşünülmüştür.

Anahtar Kelimeler:

Biyokimya, BOS, coryza gangrenosa bovum, hematoloji, sığır, sitoloji

Evaluation of Blood and Cerebrospinal Fluid Biochemistry, Cytology and Haematological Parameters in Head-and-Eye Form of Malignant Catarrhal Fever in Cattle

In this study, it was aimed to examine the biochemical changes, hematological changes and cerebrospinal fluid (CSF) cytology and blood serum of cattle with head-eye form of Malignant Catarrhal Fever (MCF). For this pur- pose, 22 cattle diagnosed with "head-eye form" of MCF and clinically healthy 10 cattle were evaluated. Blood and cere- brospinal fluid (CSF) were collected from all cattle. In sera, AST, urea, glucose, CK (P<0.05), LDH levels (P<0.01) were found be high, ALT, ALP, cholesterol (P<0.05), Ca, total protein (P<0.01) and Mg, albumine and Fe levels (P<0.001) were found to be low in MCF group when compared to the control group. In CSF, Ca (P<0.01) and total protein levels (P<0.001) were found high glucose level (P<0.05) was found low in MCF group when compared to the control group. In haematology, some parameters were determined to be different between the groups. In cytological results of CSF in MCF group, polymorphonuclear leucocytes, lymphocytes, erytrocytes, macrophages and plasma cells were determined. In conclusion, since there were a limited number of studies examining biochemical, cytologic and hematological results of MCF especially in CSF, the results from our study were thought to be important for future stud- ies in which viral diseases affects the nervous system of cattles.

Keywords:

Biochemistry, cattle, CSF, cytology, haematology, malignant catarrhal fever,

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