saime SAĞIROĞLU, SELMAN SARICA, NAGİHAN BİLAL, İSRAFİL ORHAN, AYŞEGÜL ERDOĞAN, Metin KILIÇ

Patolojik servikal lenfadenopatili çocuklarda nötrofil/lenfosit ve trombosit/lenfosit orantılarının aratırılması

Patolojik servikal lenfadenopatili çocuklardanötrofil/lenfosit ve trombosit/lenfosit orantılarınınaraştırılmasıAmaç: Bu çalışmada, bilinmeyen etiyolojili patolojik lenfadenopati(LAP) nedeniyle takip edilen, hematolojik muayeneleri normal çocuklarda nötrofil/lenfosit (NLO) ve trombosit/lenfosit orantılarının(TLO) yararlı olup olmadığının açıklığa kavuşturulması amaçlanmıştır. Yöntem:Muayene sırasında saptanan herhangi bir neden olmaksızınboyunda şişme şikayetiyle 2014 ile 2017 yılları arasında KBB kliniğine kabul edilen ve idiyopatik patolojik LAP tanısı konulan toplam 100çocuk retrospektif çalışmaya dahil edildi. Kontrol grubu herhangi birenfeksiyonu olmayan ve muayene ve laboratuvar tahlillerine göre sağlıklı olduğu düşünülen 100 çocuktan oluşmaktaydı. Hastalar ve kontrol grubu klinikteki hasta kayıtlarına bakılarak yaş, cinsiyet, kliniköykü, hastalık süreci ve muayene bulguları açısından tarandı. Bulgular:Hasta grubunda ortalama lökosit ve lenfosit sayıları kontrolgrubundan daha yüksek olup farklılık istatistiksel olarak anlamlıydı (sırasıyla p=0.008 ve p=0.001). Hasta grubunda ortalama NLO ve TLO değerleri kontrol grubuna göre anlamlı derecede daha düşüktü (sırasıylap=0.009 ve p=0.020). Sonuç:Bilinmeyen etiyolojili patolojik servikal LAP nedeniyle takipedilen çocuklarda NLO ve TLO enflamasyonla iyi bir korelasyon gösterebilir.

The investigation of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in children with pathological cervical lymphadenopathy

Objective:To reveal whether if neutrophil to lymphocyte ratio (NLR)and platelet to lymphocyte ratio (PLR) rates are useful or not in children followed-up due to pathological cervical lymphadenopathy (LAP)of unknown etiology who have a normal hematologic examination. Methods:A total of 100 children admitted to the otorhinolaryngologyclinic between 2014 and 2017 with the complaint of swelling in the neckwithout any etiology revealed on examination and established with thediagnosis of idiopathic pathological LAP were retrospectively includedin the study. The control group consisted of 100 children who did nothave any infectious condition and could be considered healthy in termsof examination and laboratory findings. Patients' and the control group'sage, gender, clinical history, disease course and examination findingswere screened from the patients' records in the clinic. Results: Mean white blood cell and lymphocyte count parameters in thepatient group were higher than the control group, and the difference wasstatistically significant (p=0.008 and p=0.001, respectively). In the patientgroup, mean NLR and PLR values were significantly lower than the control group (p=0.009 and p=0.020, respectively).Conclusion:NLR and PLR rates may be well correlated with inflammation in children followed-up due to pathologic cervical LAP withunknown etiology.

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