Mehmet Özgür AVİNÇSAL, Aytuğ ALTUNDAĞ, DENİZHAN DİZDAR, Mehmet Emre DİNÇ, Seçkin ULUSOY, Mehmet KÜLEKÇİ

Alerjik rinitte kemosensöryal bozukluklar>n de¤erlendirilmesi

Alerjik rinitte kemosensöryal bozukluklarındeğerlendirilmesiAmaç: Alerjik rinit (AR) bireylerin yaflam kalitesini hatırı sayılır derecede etkileyen ve dünya ölçeğinde sık görülen bir enflamatuvar hastalıktır.AR'nin dünya ölçeğinde genel popülasyonun %10-25'ini etkilediği tahmin edilmektedir. Hem tat alma hem de koku alma bozuklukları sosyalaktiveleri ve mesleki performansları etkileyerek AR'den rahatsız hastaların yaflam kalitesinin bozulmasına yol açmaktadır. Bu sorunların geçmiflte yeterince arafltırılmadığını düflünmekteyiz. Bu nedenle AR'den rahatsız hastalarda koku ve tat alma bozukluklarını değerlendirmeye karar verdik. Amacımız alerjik AR hastalarında kimyasal duyumsama algısını değerlendirmekti.Yöntem:Bu çalıflmaya 54 AR hastası ve 34 sağlıklı kontrol alınmıfltır.Kimyasal duyumsama değerlendirmesi için kokulu çubukları koklamave tat stripleri kullanılmıfltır. Bulgular:Kokulu çubukları koklama testi sonuçlarına göre AR hastalarının koku eflik ve tanımlama testleri skorları anlamlı derecede düflük olupiki grup arasında koku ayrım skorları açısından herhangi bir farklılık yoktu (sırasıyla p

Assessment of chemosensory disorders in allergic rhinitis

Objective:Allergic rhinitis (AR) is a globally common inflammatorydisease that has a considerable effect on an individual's quality of life.It is estimated that AR affects 10% to 25% of the general population.Both gustatory and olfactory disorders affect the social activities andjob performance resulting in impaired quality of life in patients suffering from AR. We think that these problems have not been sufficiently investigated in the past. We, therefore, decided to evaluate thesmell-taste disorders in patients suffering from AR. Our objective isto evaluate the chemosensory perception in patients suffering fromallergic AR. Methods:Fifty-four patients with AR and 34 healthy controls wereenrolled for the current study. "Sniffin' sticks" test and taste strips wereused for chemosensory assessment. Results: According to the "Sniffin' sticks" test results, patients with ARhad significantly lower scores for odor threshold and identification subtasks, whereas there was no difference between the two groups regardingodor discrimination scores (p<0.001, p<0.001, and p=0.3, respectively).After evaluating the taste strip test results, we found that taste scores weresignificantly low in patients with AR when compared to controls forsweet, salty, bitter and sour tastes.Conclusion:This study showed clinically important deficiency ofchemosensory sensitivity in AR patients. Since chemosensory deprivation in AR patients has tended to be overlooked in the past, theseoutcomes suggest that chemosensory disorders should be part of thestandard evaluation of patients with AR.

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