Multipl Myelom Hastalarında Güncel Tedavi Önerileri ve Semptom Yönetimi

Hematolojik malignensiler arasında yer alan Multipl Myelom, uygulanan tedaviler sonucunda sağkalımı, yaşam kalitesini, fiziksel, sosyal ve psikolojik durumu olumsuz yönde etkileyen önemli bir sağlık sorunudur. Multipl Myelom hastalarının tedavisinde kemoterapi, immünomodülatör ajanlar ve kök hücre nakli gibi tedavi seçenekleri kombinasyonlar halinde bulunmaktadır. Kök hücre nakli için uygun bulunan hastalarda ilk tedavi seçeneği olarak Lenalidomid, nâkile uygun bulunmayan hastalarda immünomodülatör ajan ve steroid tedavisi kullanılması önerilmektedir. Multipl Myelomda hiperkalsemi, böbrek yetmezliği, anemi ve kemik lezyonları en sık görülen semptomlar arasında yer almaktadır. Hastanın semptom yönetiminde; kan kalsiyum düzeyi izlemi, hiperkalsemi tedavisi, böbrek fonksiyonlarının izlemi, yeterli hidrasyonun sağlanması, ilaçların böbrek dozuna göre uygulanması, anemi izlemi ve tedavisi, beslenmenin desteklenmesi ve hastaların travma oluşturabilecek fiziksel aktivitelerden kaçınması önerilmektedir. Sağlık profesyonellerinin Multiple Myelomda hastalık ve tedavi ilişkili kanıta dayalı güncel tedavi önerilerini takip etmesi, semptomların önlenmesi, hastaların tedavi uyumlarının, yaşam kalitelerinin ve sağkalımlarının artırılması açısından çok önemlidir. Bu derleme Multipl Myeloma hastalarında güncel tedavi önerileri, semptom yönetimi ve hemşirelik girişimlerinin değerlendirilmesi amacıyla yapılmıştır.

Current Treatment Recommendations and Symptom Management in Patients with Multiple Myeloma

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