AYSUN AVŞAR, Gül Seda YÜCEL, CANAN ALBAYRAK

Çocuklarda Akut Lenfoblastik Lösemi Tedavisinin Dental Gelişim Üzerine Etkisinin İncelenmesi

Amaç: Çalışmanın amacı çocuklarda Akut Lenfoblastik Lösemi (ALL) tedavisinin dental yaş üzerine etkisini sağlıklı çocuklarla karşılaştırarak incelemektir. Yöntem: Ondokuz Mayıs Üniversitesi Pedodonti Anabilim Dalına tedavi amacıyla başvuran ALL tedavisi tamamlanmış yaş aralığı 4-14 olan 47 ALL hastası çalışma grubunu, aynı yaştaki ve cinsiyetteki 47 sağlıklı çocuk kontrol grubunu oluşturmuştur. Dental sebeplerle alınan panoromik radyografilar üzerinde Demirjian yöntemi kullanılarak dental yaş belirlenmiştir. Her radyografi iki değerlendirici tarafından incelenerek değerlendirme hatası minimalize edilmiştir. Gruplar arası farklılığı belirlemek için bağımsız T-testi uygulanmıştır. Sonuçların istatistiksel önemlilik düzeyi p < 0.05 olarak belirlenmiştir Bulgular: Panoramik radyografilerde Demirjian metoduyla dental yaş hesaplandığında, her iki grupta da cinsiyetler arasında dental ve kronolojik yaşın istatistiksel olarak farklı olmadığı belirlenmiştir. Kontrol grubuyla kıyaslandığında ALL tedavisi gören çocukların dental yaşının istatistiksel olarak anlamlı şekilde daha yüksek olduğu saptanmıştır. Kemoterapiyle birlikte radyoterapi uygulanan grupta dental yaşın, sadece kemoterapi uygulanan gruba göre yüksek olduğu, ancak aradaki farkın istatistiksel olarak anlamlı olmadığı saptanmıştır. Sonuç: ALL tedavi uygulanan çocuklarda kemoterapi ve radyoterapi içeren tedavi protokolü dental yaş üzerinde etkili olduğu saptanmıştır

The Effect of Treatment of Acute Lymphoblastic Leukemia on Dental Maturity in Children

Objective: The purpose of this study is to study the effect of Acute Lymphoblastic Leukemia (ALL) on dental age by comparing the same in healthy children. Methods: 47 ALL patients aged between 4-14 years and 47 healthy children of the same age and sex composed the study group. Dental age of the patients was determined by Demirjian method using panoramic radiographs taken for dental purposes. To minimize the error, each radiograph was evaluated by two dentists. To determine the difference between the groups independent T-test was done. Statistical significance level was chosen as p

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