Sosyoekonomik düzeyi düşük çocuklardaki toplum kaynaklı pnömonilerde A vitamini ve çinko düzeyleri

Giriş: Çocukluk çağında pnömoniden korunma önlemleri içinde besinsel faktörler, çinko ve A vitamini desteğinin yapılması, pasif sigara içiminin engellenmesi, sosyoekonomik durumun iyileştirilmesi ve aşılanma bulunmaktadır. Bu çalışmada amaç, toplum kaynaklı pnömoni tanısıyla kliniğimize yatan çocukların besinsel ve sosyal faktörleri araştırmak, serum A vitamini ve çinko düzeylerini belirlemektir. Gereç ve Yöntem: Hastanemiz Çocuk Kliniğine Ocak 2006-Ocak 2007 tarihleri arasında toplum kaynaklı pnömoni teşhisiyle izlenen 60 çocuk, kesitsel olarak çalışmaya alındı. Bulgular: Olguların 30'u (%50) kız, ortalama yaş 3.7±3.6 yıl (min-max:1 ay-14 yıl) idi. Olguların %73.3'ünün sosyoekonomik seviyesi düşüktü. Evde pasif sigara içimi %38.3'ünde mevcuttu ve %33.3'si altı aydan daha kısa süre anne sütü almıştı. Ortalama serum A vitamini düzeyi 1.0±0.5 µmol/L (min-max: 0.2-2.4) ve çinko düzeyi 15.4±5.1 µmol/L (min-max:8.9-31.5) saptandı. Vitamin A 18 (%30) ve çinko 5 (%8.3) olguda düşük bulundu. Vitamin A düşüklüğü ile yeşil sebze ve meyve tüketiminin az olması arasında ilişkili saptandı (p=0.002). Çinko düşüklüğü 0-2 yaş grubundaki çocuklarda saptandı (p=0.01). Olgulardan hiçbirinde malnütrisyon saptanmadı, ancak hastanede yedi günden uzun yatanların ağırlık persentilleri daha düşüktü (p=0.09). Sonuç: Pnömonili çocuklara A vitamini desteği yapılmasını öneriyoruz. Sıfır-iki yaş grubundaki çocukların çinko eksikliği yönünden değerlendirilmesi gerekmektedir. Pasif sigara içimi önlenmeli, anne ve toplum eğitimi üzerinde durulmalıdır.

Vitamin A and zinc levels in socioeconomically disadvantaged children with community-acquired pneumonia

Introduction: Among preventive measures from childhood pneumonia nutritional factors, supplementation zinc and vitamin A, preventing passive smoking, improving socioeconomic conditions and immunization exist. We aimed to determine the nutritional status, investigate social conditions, frequency of vitamin A and zinc deficiencies in children which were hospitalized with the diagnose of community-acquired pneumonia. Materials and Methods: Sixty children, who were hospitalized during January 2006 to January 2007, were included in the study, by cross-sectional method. Results: Thirty (50%) were girls. Mean age was 3.7±3.6 years (min-max: 1 month-14 years). Socioeconomic levels were low in 73.3%, 38.3% were passive smokers and 33.3% were breast-fed less than six months. Mean levels of vitamin A were 1.0±0.5 µmol/L (min-max: 0.20-2.35), and zinc were 15.4±5.1 µmol/L (min-max: 8.9-31.5). Vitamin A levels were low in 18 (30%) and zinc in 5 (8.3%). Low vitamin A levels were associated with inadequate fruit and vegetable consumption (p=0.002). Low zinc levels were seen in 0-2 year group (p=0.01). Malnutrition was not determined in any case. Lower weight and height percentiles were associated with longer hospital stay (p=0.09). Conclusions: Vitamin A supplementation was offered to children with pneumonia. Also, zinc deficiency should be considered in infancy. Passive smoking should be prevented, education of mothers and population is crucial.

___

  • 1) Rudan I, Tomaskovic L, Boschi-Pinto C, Campbell H; WHO Child Health Epidemiology Reference Group. Global estimate of the incidence of clinical pneumonia among children under five years of age. Bull World Health Organ. 2004;82:895-903
  • 2) Zar HJ, Madhi SA. Childhood pneumonia-progress and challenges. S Afr Med J. 2006;96:890-900
  • 3) Kendirli T, Derelli E, Özdemir H, İnce E. Çocuk yoğun bakım ünitesinde mekanik ventilatörde izlenen hastaların retrospektif değerlendirilmesi. Gülhane Tıp Dergisi. 2004;46:287-90
  • 4) Kılıç S, Tezcan S, Taşçılar ME ve ark. GATA Çocuk Sağlığı ve Hastalıkları Anabilim Dalı yataklı servislerinde 2001 yılında tedavi gören hastaların tanı ve tedavi özellikleri. Gülhane Tıp Dergisi. 2003;45:169-74
  • 5) Lopez A. Malnutrition and burden of disease. Asia Pac J Clin Nutr. 2004;13:7
  • 6) Vitamin A supplementation advices and guidelines presented by World Health Organization. İnternet adresi: www.who.int/vaccines/en/vitamina.shtml
  • 7) West KP. Extent of vitamin A deficiency among preschool children and women of reproductive age. J Nutr. 2002;132:2857-66
  • 8) Miller M, Humphrey J, Johnson E, et al. Why do children become vitamin A deficient ? J Nutr. 2002;132:2867-80
  • 9) Müller O, Krawinkel M. Malnutrition and health in developing countries CMAJ 2005;173:279-86
  • 10) Villamor E, MD, Mbise R, Spiegelman D, et al. Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth. Pediatrics. 2002;109(1):E6
  • 11) Black RE. Zinc deficiency, infectious disease and mortality in the developing World. J Nutr. 2003.133:1485-9
  • 12) Man WD, Weber M, Palmer A, et al. Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa. Trop Med Int Health. 1998;3:678-86
  • 13) Banajeh SM. Outcome for children under 5 years hospitalized with severe acute lower respiratory tract infections in Yemen: a 5 year experience. J Trop Pediatr. 1998;44:343-6
  • 14) Kaushik K, Singh JV, Bhatnagar M, et al. Nutritional correlates of acute respiratory infections. Indian J Matern Child Health. 1995;6:7-12
  • 15) Kocabaş E, Yalçın E, Akın L ve ark. Toraks Derneği çocukluk çağında toplum kökenli pnömoni tanı ve tedavi rehberi 2002. Toraks Dergisi. 2002:3; 17-27
  • 16) Hassan MK, Al-Sadoon I. Risk factors for severe pneumonia in children in Basrah. Trop Doct. 2001;31:139-41
  • 17) Lanata FC, Rudan I, Boschi-Pinto C, et al. Methodological and quality issues in epidemiological studies of acute lower respiratory infections in children in developing countries. IJE 2004;33:1362-72
  • 18) Cherian T. Describing the epidemiology and aetiology of bacterial pneumonia in children: an unresolved problem. J Health Popul Nutr. 2005;23:1-5
  • 19) Nickolson JF, Pesce MA. Reference ranges for laboratory tests and procedures. In: Behrman RE, Kliegman R M, Jenson HB, eds. Nelson textbook of pediatrics 17. baskıth edition. Philadelphia:W.B. Saunders;2004. p.2396-427
  • 20) Nüfus ve kalkınma göstergeleri Hanehalkı Bütçe Anketi, 2003. T.C Başbakanlık DİE web sitesi: http//www.die.gov.tr
  • 21) Kurugol Z, Egemen A, Keskinoglu P, et al. Vitamin A deficiency in healthy children aged 6-59 months in İzmir Province of Turkey Paediatr Perinat Epidemiol. 2000;14:64-9
  • 22) Sandstead HH. Zinc deficiency. A public health problem? Arch Pediatr Adolesc Med. 1991;145:853-9
  • 23) Boran P, Tokuc G, Vagas E, et al. Impact of zinc supplementation in children with acute diarrhoea in Turkey. Arch Dis Child. 2006;91:296-9
  • 24) Kumar S, Awasthi S, Jain A, Srivastava RC. Blood Zinc levels in children hospitalized with severe pneumonia: a case control study. Indian Pediatr. 2004;41:486-91
  • 25) Bhandari N, Bahl R, Taneja S, et al. Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum. BMJ. 2002 ; 324(7350): 1358
  • 26) Gergen PJ, Fowler JA, Maurer KR, et al. The burden of environmental tobacco smoke exposure on the respiratory health of children 2 months through 5 years of age in the United States: Third National Health and Nutrition Examination Survey, 1988 to 1994. Pediatrics. 1998;101(2):p.e8
  • 27) César JA, Victora CG, Barros FC, et al. Impact of breast feeding on admission for pneumonia during postneonatal period in Brazil: nested case-control study. BMJ. 1999;318:1316-20
Ege Tıp Dergisi-Cover
  • ISSN: 1016-9113
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1962
  • Yayıncı: Ersin HACIOĞLU