Evaluation of Intraocular Pressure and Central Corneal Thickness Changes After Hemodialysis In Patients With Chronic Renal Failure

This study evaluated short-term changes in intraocular pressure (IOP) and corneal thickness (CCT) following haemodialysis (HD) in chronic renal failure (CRF) patients. We studied 34 eyes of 34 patients with CRF undergoing HD. Patients included in the study were classified into two subgroups: group 1 (with DM) and group 2 (non-DM). All patients underwent a detailed ophthalmological examination including CCT and IOP before and after the HD session. Total body weight and body volume loss after haemodialysis were also measured. The sex distribution of patients were 22 female (64.7%) and 12 male (35.3%). The DM group was comprised of 15 patients (44.1%), and the non-DM group had 19 patients (55.9%). The mean age was 60.3 ± 17.2 (range 21–88) years, and the dialysis time was 51.4 ± 38.5 (range 5–132) months. The mean IOP change after HD decreased from 15.88±2.37 to 14.11±2.02 mmHg (95% CI, 1.40–2.11; p < 0.001). The mean CCT decreased from 554.88±14.27 to 550.52±13.67 μm. (95% CI, 1.97–4.08; P = p < 0.001). The loss in body volume was positively correlated with a decrease in IOP (r = 0.737, p < 0.001) and CCT (r = 0.784, p < 0.001). In patients with CRF who have glaucoma, visual acuity may be adversely affected by IOP and CCT changes following HD. Therefore, a detailed ophthalmologic examination should be performed to take preventive measures for at-risk patients before and after HD.

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