Hayrettin ÖZTÜRK, Kazim KARAARSLAN, Fahri YILMAZ, Hülya ÖZTÜRK

Infantil fibröz hamartom: Immunohistopatolojik bir çalisma

Infantil fibröz hamartom (IFH) yüzeyel bir kitle olarak olusan nadir bir lezyondur. Burada inguinal bölgede fibröz hamartomlu bir olgu sunuldu. IFH’li çocugun klinik ve histopatolojik özellikleri ve tedavi sonuçlari tanimlandi ve literatürle degerlendirildi. Histopatolojik özellikleri miyofibroblast demetlerinin varligi, disorganize matür adipozitler ve küçük yuvarlak yassi primitif mezenkimal hücrelerin varligini içerdi. Immunohistokimyasal olarak miyofibroblastik komponent aktin ile vimentin, primitif komponentin ise sadece vimentin içermekteydi. Çocuklarda nadir olarak görülen bu patolojinin tedavisi komplet eksizyondur

Anahtar Kelimeler:

Infantil fibröz hamartom, yumusak doku tümörü, miyofibroblast, pirimitif mezenkimal hücreler, desmin, aktin

Fibrous hamartoma of infancy: An immunohistopatologyc study

Fibrous hamartoma of infancy (FHI) is an uncommon lesion, occurring as a superficial mass. We present one case of fibrous hamartoma in the ingunal region. The clinical and histopathologic features, and treatment results of child with (FHI) were described and the literature was reviewed. Criteria for histologic diagnosis include the presence of fasicles of myof ibroblasts, disorganized mature adipocytes and small rounded primitive mesenchymal cells. Immunohistochemically, muscle specific actin and vimentin were expressed in the myofibroblastic component, and vimentin was only expressed in the primitive component. The treatment of this uncommonly seen pathology is completely excision

Keywords:

Fibrous hamartoma of infancy, soft tissue tumor, myofibroblasts, primitive mesenchymal cells, desmin, actin,

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