Belirtisiz Bir Hepatit A Enfeksiyonu Olgusu

Hepatit A virüs infeksiyonu gelismekte olan ülkelerde özellikle çocuklarda sik görülen bir infeksiyondur. Oral-fekal yolla bulasan hastalikta kisisel temas çok önemlidir. Aile hekimligi poliklinigine basvuran 11 yasinda bir kiz çocugunda, 25 gün önce hepatit A geçiren bir arkadasiyla temas öyküsü mevcuttu. Temastan 15 gün sonra hastada soguk alginligini animsatan sikayetler gelismisti. Yapilan laboratuvar incelemelerinde anti-HAV IgM pozitifligi disinda anormal bir deger bulunamadi. Bir yil boyunca düzenli araliklarla rutin takibe alinan hastanin biyokimyasal tetkikleri sürekli olarak normal bulundu. Hastaligin baslangicindan itibaren pozitif olan anti-HAV IgM’in 12. ayda negatiflestigi saptandi. Literatür incelemesinde temas sonrasi gelisen hepatit A olgusu saptanamadigi için mevcut olgu sunulmaya deger bulundu

A Case of Asymptomatic Hepatitis A virus infection

Hepatitis A infection is a common infectious disease seen especially in children of developing countries. Personal contact is very considerable among the fecal-oral contagious diseases. A 11-yearsold girl, referring to outpatient clinics of department of family medicine, has the history of contact with her hepatitis A infected friend. Flu-like symptoms arose in 15 days after the contact. Any abnormal parameter except anti-HAV Ig M positiveness wasn’t detected in the laboratory studies. Biochemical parameters were reported as normal during the one-year period of routine control. It was assigned that anti-HAV Ig M, being positive since the beginning of the disease, turned to negative in the 12th month. Because no hepatitis A case after a contact history was established in the literature, existing case was distinguished to present

___

  • Feinstone SM, Gust ID: Hepatitis A Virus. In Mandell GL, Bennett JE, Dolin R, (eds): Principles and Practice of Infectious Diseases. 5th edition. Philadelphia. Elsevier. pp: 1920– 1940, 2000.
  • Lemon SM, Martin A: Hepatitis A Virus In Gorbach SL, Bartlett JG, Blacklow NR (eds): Infectious Diseases: 3th edition. Philadelphia. Lippincott Williams & Wilkins. pp: 2063– 2071, 2004.
  • Aygen B. Hepatit A Virüsü. Willke TA, Söyletir G, Doganay M: Infeksiyon Hastaliklari ve Mikrobiyolojisi. 2. baski. Istanbul. Nobel kitabevleri. pp: 1340–139, 2002.
  • Lee KK, Biodget JB. Screening travelers for hepatitis A antibodioes. West J Med. 173: 325– 329, 2000.
  • Lemon SM: Type A viral hepatitis: epidemiology, diagnosis, and prevention. Clinical Chemistry. 43:1494–1499, 1997.
  • Jong EC: United States epidemiology of hepatitis A: influenced by immigrants visiting friends and relatives in Mexico? Am J Med. 118: 505–575, 2005.
  • Aytaç S, Kargili A, Türkay C: A prolonged gestational intrahepatic cholestasis: A case report. Turk J Gastroenterol. 17: 206–208, 2006.
  • Ciocca M: Clinical course and consequences of hepatitis A infection. Vaccine. 18: 71–74, 2000.
  • Tosun S: HAV enfeksiyonunda klinik ve korunma. Tabak S, Balik I, Tekeli E (eds). Viral Hepatit Kitabi 2007. 1. Baski. Istanbul. VHSD. pp: 62–93, 2007.
  • Poovorawan Y, Theamboonlers A, Chongsrisawat V, Jantaradsamee P, Chutsirimongkol S, Tangkijvanich P: Clinical features and molecular characterization of hepatitis A virus outbreak in a child care center in Thailand. J Clin Virol. 32: 24– 8, 2005.