Yasemin Ateş TÜTÜNCÜ, Funda CERAN, Seyfettin KÖKLÜ, Mehmet YILDIZ, Gökhan CELBEK, Yusuf AYDIN

Helikobakter Pylori Enfeksiyonu B12 Eksikliğinin Gerçekten Bir Nedeni midir?

Amaç: Bu çalışmanın amacı vitamin B12 eksikliğindeki H. pylori enfeksiyonu oranını ve h.pylori enfeksiyonunun gerçekten vitamin B12 eksikliğinin asıl sebebi olup olmadığınıbelirlemektir.Materyal ve Metod: 40 vitamin B12 eksikliği olan hastayı ve 25 sağlıklı kişiyi değerlendirdik.Bu hastaların B12 eksikliği sebebi bilinmiyordu. H. pylori için endoskopik değerlendirme vepatolojik inceleme uyguladık. Vitamin B12 eksikliği olan grupta %50 atrofik gastrit belirledik,fakat kontrol grubunda endoskopik olarak hiçbir atrofik gastrit gözlemlemedik.Bulgular: Patolojik incelemelere göre hasta grubunda 40 hastadan 11’inde (%27,5), kontrolgrubunda ise 25 hastadan 16’sında (%64) H. pylori pozitifliği vardı (p

Anahtar Kelimeler:

Vitamin B12 eksikliği, H.pylori, gastrik atrofi

Is Helicobacter Pylori Infection One of the Actual Causes of Vitamin B12 Deficiency?

Aim: Aim of this study is to determine Helicobacter pylori infection rate in Vitamin B12deficiency and determine whether H.pylori infection is really actual cause of Vitamin B12deficiency.Material and Methods: We evaluated 40 vitamin B12 deficient patients and 25 healthy subjects.Those patients did not have known cause of vitamin B12 deficiency. We performed endoscopicevaluation and pathological examination for H.pylori. We determined 50% atrophic gastritis invitamin B12 deficient group, but we did not observe any atrophic gastritis in the control groupendoscopically.Results: There were H.pylori positivity in 11/40 (27.5%) in the patients group but 16/25 (64)in the control group in pathological examination (p

Keywords:

Vitamin B12 deficiency, H.pylori, gastric atrophy,

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