ÖZLEM ÖZBAĞÇIVAN, Sevgi AKARSU, Emel FETİL

Tip II Diabetes Mellitus Ve Tiroid Hastalarında Gözlenen Deri Bulguları ve Karşılaştırılması

Amaç: Diabetes Mellitus (DM) ve Tiroid Hastalıkları (TH) sık görülen kronik metabolik hastalıklardır. Bu hastalıkların tanısı, seyri ve komplikasyonları ile ilgili yardımcı belirtiler olabileceğini düşündüğümüz dermatolojik bulguları araştırmak amacıyla araştırmamıza Tip II DM veya TH tanısı olan olgular alınmıştır. Yöntemler: Araştırmaya Tip II DM (n=100) veya TH (n=100) tanısı olan olgular alınarak ayrıntılı bir dermatolojik muayeneden geçirilmiştir. Tüm olguların dosyaları, demografik verileri, hastalığa özgün öyküleri, eşlik eden hastalıkları, medikasyonları ve laboratuar bulguları açısından retrospektif olarak taranmıştır. Bulgular: DM grubunda en sık gözlenen dermatolojik bulgular fibroma molle (%51), onikomikoz (%38) ve hemangioma (%33); TH grubunda ise tırnak bulguları (%64), saç dökülmesi (%45), kserozis (%37) ve plantar hiperkeratoz (%37) olarak belirlenmiştir. Onikomikoz ve tinea pedis DM grubunda (p=0,030, p=0,003), tırnak bulguları (p=0,001) ve saç bulguları (p=0,001) ise TH grubunda daha fazla oranda izlenmiştir. Sonuç: Özellikle ileri yaş grubundaki diyabetli hastalarda önemli morbidite ve mortalite nedeni olan mikotik infeksiyonlar araştırmamızda yüksek oranlarda saptanmıştır. DM hastalarında mikotik infeksiyonlar dermatolojik muayenenin rutin bir parçası olmalıdır. Bunun yanında saç dökülmesi, saç yapısında değişiklikler ve tırnak bulguları ile dermatoloji polikliniklerine başvuran olguların klinik ve laboratuvar incelemeler ile tiroid hastalıkları açısından araştırılması uygun olacaktır

SKIN FINDINGS AND THEIR COMPARISION IN PATIENTS WITH TYPE II DIABETES MELLITUS AND THYROID DISEASE

Objective: Diabetes Mellitus (DM) and Thyroid Disease (TD) are common chronic metabolic disorders. Patients with Type II DM or TD were inrolled in our study to determine dermatological findings which may be associated with the diagnosis, prognosis and complications of these diseases. Methods: Type II DM (n=100) and TD (n=100) patients were enrolled in the study and a detailed dermatological examination was done. The files of all patients were retrospectively reviewed in terms of demographic data, disease-specific history, accompanying diseases, medications and laboratory findings. Results: The most frequently observed dermatological findings were fibroma molle (%51), onicomycosis (%38) and hemangioma (%33) in DM group and nail findings (%64), hair loss (%45), xerosis (%37) and plantar hyperkeratosis (%37) in TD group. While onicomycosis (p=0,030) and tinea pedis (p=0,003) were more frequent in DM group, nail (p=0,001) and hair findings (p=0,001) were more frequent in TD group. Conclusion: Mycotic infections which cause significant morbidity and mortality especially in older diabetic patients were determined at higher rates in our study. Screening for mycotic infections in patients with DM should be a routine part of the dermatological examination. In addition we assumed that it would be more appropriate to research for thyroid disease in patients presenting with signs and symptoms of hair loss, changes in the structure of hair and nails

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