Erhun KASIRGA, İpek AKİL, Dilek YILMAZ, Filiz BAŞARIR, Semin AYHAN

Ödem ve kilo kaybı ile başvuran seranegatif bir gluten enteropatisi olgusu

Atipik bulgularla ortaya çıkan gluten enteropatisi olgularında tanı konulması oldukça zordur. Ancak günümüzde serolojik testlerin kullanımı sayesinde biyopsi yapılacak olguların seçimi kolaylaşmıştır. Burada ödem ve kilo kaybı yakınmaları ile başvuran, serolojik testleri (anti-endomysial IgA, anti-gliadm IgA ve IgG) negatif olan ve duodenal biyopsi ile gluten enteropatisi tanısı konulan 10 yaşında bir kız çocuğu sunuldu. Glutensiz diyete başlandıktan sonra hastanın ödemi kaybolurken, hızlı kilo akını gözlendi. Sonuç olarak belirgin gastrointestinal bulguları bulunmayan ve serolojik testleri negatif olan hastalarda bile gluten enteropatisi kuşkusu varsa duodenal biyopsinin mutlaka yapılması gerektiği düşünüldü.

Anahtar Kelimeler:

Çölyak hastalığı, Çocuk, Ödem, Kilo kaybı

The seronegative gluten enteropathy case presented with edema and loss of weight

Diagnosis of gluten enteropathy in cases with atypic symptoms is very difficult. But nowadays selection of cases for biopsy becomes more easy by the use of serologic tests. We presented 10 years old girl, with complaints of edema and loss of weight whom serologic tests were negative (anti-endomysial IgA, anti-gliadin IgA and IgG) and diagnosis of gluten enteropathy made by duodenal biopsy. After the use of gluten free diet, edema dissapeared while rapid weight gain was observed. In conclusion, it has been suggested that in the case of suspicion of gluten enteropathy without obvious gastrointestinal symptoms and negative serologic tests, duodenal biopsy should be done.

Keywords:

Celiac Disease, Child, Edema, Weight Loss,

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