Nazan UYSAL, Kazım TUĞYAN, Osman AÇIKGÖZ

Kemirgende ve insanda beyin gelişimi

Erişkin dönemde bazı özel beyin bölgelerinde yeni hücre oluşabilmesine rağmen, memelilerde beyin gelişiminin genel olarak embriyonik dönemde başlayarak adölesan dönemin sonuna kadar devam ettiği kabul edilmektedir. Kemirgen ve insan beyni arasında önemli farklılıklar olmasıyla birlikte genel yapılanma birbirine benzer. Ancak, gelişimleri birbirinden oldukça farklıdır. Kemirgenlerde daha çok doğumdan sonraki gelişim önemli iken insanda gelişimin büyük bir bölümü intrauterin dönemde şekillenir. Bunun yanı sıra beyin gelişim süreci, kemirgenlerde günlerle, insanlarda haftalarla veya aylarla ifade edilir. Bu konuda çalışacak araştırıcıların gelişim dönemlerine dikkat etmesi ve deneyleri buna göre planlanmaları uygun olacaktır. Bu yazıda, sıçan beyninin fiziksel ve fonksiyonel gelişiminin insan beyniyle karşılaştırılarak özetlenmesi amaçlanmıştır.

Anahtar Kelimeler:

Beyin, Rodentia, Sinir sistemi

Brain development in rodents and humans

Brain development of mammalian begins in embryonic period and continues until the end of the adolescence, despite occur new cells in adult period. The normal ontogeny of neural development in rodents is different from humans, but general gross structure of the brains of rodents and humans is similar. But, properties of brain development of these species are very different. While postnatal brain development is more important in rodents, development in human brain is over in intrauterin stage. However, brain development of the rodent proceeds on a timeline of days versus weeks to months in humans. In further studies, researchers should consider for the developmental stages in their study design. The aim of this article is to describe similarities and differences of physically and functionally developmental processes of brain between rodents and humans.

Keywords:

Brain, Rodentia, Nervous System,

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