Nizamettin Selçuk YELGEÇ, Mehmet Baran KARATAŞ, Can Yücel KARABAY, Yiğit ÇANGA, Ali Nazmi ÇALIK, Barış ŞİMŞEK, Özge GÜZELBURÇ, Ayşe MERE

Transkateter Aort Kapak Replasmanı Sonrası Gelişen Akut Böbrek hasarı ile İşlem Öncesi Nötrofil Lenfosit Oranı Arasındaki İlişki

Giriş: Transkateter aort kapak replasmanı (TAVR), cerrahi aort kapak replasmanına alternatif olarak, ciddi aort stenozu olan yüksekcerrahi riskli hastalar için günümüzde kabul görmüş ve gelişen bir tedavi seçeneğidir. Akut böbrek hasarı (ABH), TAVR sonrası sık görülen bir komplikasyon olup daha kötü sonuçlarla ve sağ kalımla ilişkilidir. Bu çalışmanın amacı TAVR yapılan hastalarda, işlem öncesi serum nötrofil lenfosit oranı (NLR) ile işlem sonrası gelişen ABH arasındaki ilişkiyi araştırmaktır. Yöntemler: Kurumumuzda 2010- 2018 tarihleri arasında TAVR uygulanan 148 hastanın retrospektif analizi yapılmıştır. Hastalar iki gruba ayrılmıştır. Grup 1 (n = 116): TAVR uygulanan ancak ABH gelişmeyen kontrol grubu hastalar; Grup 2 (n = 32): TAVR sonrası ABH gelişen hastalar. Veriler akut böbrek hasarının olası bağımsız belirteçlerini tespit etmek için regresyon analizi yöntemi ile analiz edilmiştir. Bulgular: Bu çalışmada 32 hasta da (%22) TAVR sonrası ABH gelişmiştir. Nötrofil lenfosit Oranı, ABH gelişimi ile anlamlı olarak ilişkili (3.22 ±0.62 vs. 2.42 ± 0.45, p

The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio

Objective: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to open-heart surgery forpatients with severe symptomatic aortic stenosis who has a high risk for surgery. Acute kidney injury (AKI) is not a rarecomplication after TAVR and has been associated with poorer outcomes and survival. This study aims to analyze therelation between serum Neutrophil-lymphocyte ratio (NLR) and AKI in Post-TAVR patients.Methods: 148 patients who have been performed TAVR at our institution between 2010 and 2018, analyzedretrospectively. We divided the patients into two groups. Group 1 (n=116): The patients who did not develop AKI afterTAVR procedure (control group) and Group 2 (n=32): The patients who developed AKI after TAVR. The independentrelation between possible independent predictors of AKI in post-TAVI patients was analyzed by regression analysis.Results: 32 patients (22%) suffered from AKI after TAVR during hospitalization. NLR was significantly associated withthe development of AKI (3.22 ±0.62 vs. 2.42 ± 0.45, p

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