Ali BAY, Vuslat BOŞNAK, Enes COŞKUN, Ali Seçkin YALÇIN, Hatice UYGUN, Şamil HIZLI

Severe Rotavirus gastroenteritis in a patient with infant leukemia

Rotavirus infant ve küçük çocuklarda ağır gastroenteritin en sık nedenidir. Bağışıklığı baskılanmış çocuklarda rotavirus gastroenteritinin klinik seyrine ait bildiriler az sayıdadır. Biz, bu raporda akut miyeloblastik lösemi tanısı ile izlediğimiz hayatı tehdit edici rotavirus gastroenteriti gelişen bir infant olguyu sunarak, son zamanlarda tavsiye edilen Rotavirüs aşısına dikkat çekmek istedik.

İnfant lösemili bir hastada görülen ağır Rotavirus gastroenteriti

Rotavirus is the most common cause of severe gastroenteritis in infants and young children. Reports about the clinical relevance of rotavirus in immunocompromised children are rare. We herein presented a case of life-threatening Rotavirus gastroenteritis in an infant with acute myeloblastic leukemia which could be prevented by recently recommended Rotavirus vaccination.

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1. Zuccotti G, Meneghin F, Dilillo D,et al Epidemiological and clinical features of rotavirus among children younger than 5 years of age hospitalized with acute gastroenteritis in Northern Italy. BMC Infect Dis 2010;10:218-221.
2. Tekin A. Mardin'deki akut gastroenteritli çocuklarda Rotavirüs ve Enterik Adenovirüs sıklığı. Klin Deney Ar Derg 1; 41-45
3. Rogers M, Weinstock DM, Eagan J, Kiehn T, Armstrong D, Sepkowitz KA. Rotavirus outbreak on a pediatric oncology floor: possible association with toys Am J Infect Control 2000;28:378-380.
4. Rayani A, Bode U, Habas E, et al Rotavirus infections in paediatric oncology patients: a matched-pairs analysis. Scand J Gastroenterol 2007;42:81-87.
5. Fitts SW, Green M, Reyes J et al. Clinical features of nosocomial rotavirus infection in pediatric liver transplant recipients. Clin Transplant 1995;9:201–204.
6. Flem ET, Kasymbekova KT, Vainio K, et al. Rotavirus infection in hospitalized children and estimates of disease burden in Kyrgyzstan, 2005-2007. Vaccine 2009;27 Suppl 5:F35-39.
7. Guerrero ML, Moreno-Espinosa S, Tuz-Dzib F, et al. Breastfeeding and natural colonization with Lactobacillus spp as protection against rotavirus-associated diarrhea. Adv Exp Med Biol 2004;554:451-455.
8. Liakopoulou E, Mutton K, Carrington D et al. Rotavirus as a significant cause of prolonged diarrhoeal illness and morbidity following allogeneic bone marrow transplantation. Bone Marrow Transplant 2005;36:691-694.